U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C26H23BrFN7O3
Molecular Weight 580.408
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DANICOPAN

SMILES

CC(=O)C1=NN(CC(=O)N2C[C@H](F)C[C@H]2C(=O)NC3=CC=CC(Br)=N3)C4=CC=C(C=C14)C5=CN=C(C)N=C5

InChI

InChIKey=PIBARDGJJAGJAJ-NQIIRXRSSA-N
InChI=1S/C26H23BrFN7O3/c1-14(36)25-19-8-16(17-10-29-15(2)30-11-17)6-7-20(19)35(33-25)13-24(37)34-12-18(28)9-21(34)26(38)32-23-5-3-4-22(27)31-23/h3-8,10-11,18,21H,9,12-13H2,1-2H3,(H,31,32,38)/t18-,21+/m1/s1

HIDE SMILES / InChI

Approval Year

Name Type Language
DANICOPAN
USAN   INN  
Official Name English
DANICOPAN [JAN]
Common Name English
ACH-4471
Code English
(2S,4R)-1-(2-(3-ACETYL-5-(2-METHYLPYRIMIDIN-5-YL)-1H-INDAZOL-1-YL)ACETYL)-N-(6-BROMOPYRIDIN-2-YL)-4-FLUOROPYRROLIDINE-2-CARBOXAMIDE
Systematic Name English
danicopan [INN]
Common Name English
ACH-0144471
Code English
(2S,4R)-1-{[3-Acetyl-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl]acetyl}-N-(6-bromopyridin-2-yl)-4-fluoropyrrolidine-2-carboxamide
Systematic Name English
DANICOPAN [USAN]
Common Name English
Danicopan [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 512715
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
EU-Orphan Drug EU/3/18/1989
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
FDA ORPHAN DRUG 617117
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
Code System Code Type Description
INN
10610
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
NCI_THESAURUS
C148181
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
SMS_ID
100000175510
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
FDA UNII
JM8C1SFX0U
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
CAS
1903768-17-1
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
PUBCHEM
118323590
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
DRUG BANK
DB15401
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY
USAN
GH-91
Created by admin on Sat Dec 16 13:46:57 GMT 2023 , Edited by admin on Sat Dec 16 13:46:57 GMT 2023
PRIMARY