Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C9H7N |
| Molecular Weight | 129.1586 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C1=CC2=CC=NC=C2C=C1
InChI
InChIKey=AWJUIBRHMBBTKR-UHFFFAOYSA-N
InChI=1S/C9H7N/c1-2-4-9-7-10-6-5-8(9)3-1/h1-7H
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Isoquinoline alkaloid production by transformed cultures of Papaver somniferum. | 2001 |
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| Transfection-enforced Bcl-2 overexpression and an anti-Parkinson drug, rasagiline, prevent nuclear accumulation of glyceraldehyde-3-phosphate dehydrogenase induced by an endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol. | 2001 Aug |
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| [Pathogenesis of idiopathic Parkinson's disease]. | 2001 Jul |
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| Chemopreventive activity of isoquinoline alkaloids from Corydalis plants. | 2001 Jul |
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| Phototoxicity of azaarene isomers to the marine flagellate Dunaliella tertiolecta. | 2001 Jul |
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| Disease activated drugs: a new concept for the treatment of asthma. | 2001 Jul |
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| Vinyl imidates in cycloaddition reactions: a formal synthesis of (+/-)-reserpine. | 2001 Jul 26 |
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| Thiazole and thiadiazole analogues as a novel class of adenosine receptor antagonists. | 2001 Mar 1 |
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| PK11195, an isoquinoline carboxamide ligand of the mitochondrial benzodiazepine receptor, increased drug uptake and facilitated drug-induced apoptosis in human multidrug-resistant leukemia cells in vitro. | 2002 |
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| Homology modeling of falcipain-2: validation, de novo ligand design and synthesis of novel inhibitors. | 2002 Apr |
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| Expression of the iorAB genes from Brevundimonas diminuta 7 encoding the molybdenum hydroxylase isoquinoline 1-oxidoreductase in Pseudomonas putida. | 2002 Apr 23 |
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| Presence of isoquinoline alkaloids in molluscan ganglia. | 2002 Aug |
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| Two optically active isoquinoline derivatives. | 2002 Aug |
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| Drotaverine interacts with the L-type Ca(2+) channel in pregnant rat uterine membranes. | 2002 Aug 2 |
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| Synthesis of fluoren-9-ones by the palladium-catalyzed cyclocarbonylation of o-halobiaryls. | 2002 Aug 9 |
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| Inhibitory effect of isoquinoline alkaloids on movement of second-stage larvae of Toxocara canis. | 2002 Dec |
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| Cellular mechanisms of inhibition of superoxide anion generation in rat neutrophils by the synthetic isoquinoline DMDI. | 2002 Jan 2 |
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| Dioncophylline E from Dioncophyllum thollonii, the first 7,3'-coupled dioncophyllaceous naphthylisoquinoline alkaloid. | 2002 Jun |
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| The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase. | 2002 Mar |
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| Assay of nematocidal activity of isoquinoline alkaloids using third-stage larvae of Strongyloides ratti and S. venezuelensis. | 2002 Mar 1 |
|
| Benzoquinolines and chloride secretion in murine colonic epithelium. | 2003 Apr |
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| A new isoquinolinone derivative with noble vasorelaxation activity. | 2003 Apr |
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| Unexpected isolation, and structural characterization, of a beta-hydrogen-containing sigma-alkylpalladium halide complex in the course of an intramolecular heck reaction. synthesis of polycyclic isoquinoline derivatives. | 2003 Jan 21 |
|
| Perspective in antimalarial chemotherapy. | 2003 Jul |
|
| Beta-phenylethylamines and the isoquinoline alkaloids. | 2003 Jun |
|
| In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. | 2003 Mar |
|
| Antitrypanosomal naphthylisoquinoline alkaloids and related compounds. | 2003 May |
|
| Structure-based approach to falcipain-2 inhibitors: synthesis and biological evaluation of 1,6,7-trisubstituted dihydroisoquinolines and isoquinolines. | 2003 May 15 |
Patents
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JECFA EVALUATION |
ISOQUINOLINE
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CFR |
21 CFR 172.515
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119-65-3
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1187
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16092
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8405
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3395
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204-341-8
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C039109
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m6538
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DB04329
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ISOQUINOLINE
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DTXSID2047644
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JGX76Y85M6
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SUBSTANCE RECORD
