MERADIMATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Previously Marketed

First approved in 1970

US Previously Marketed

First approved in 1970

Details

Stereochemistry	UNKNOWN
Molecular Formula	C17H25NO2
Molecular Weight	275.3859
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MERADIMATE

Structure Search

SMILES

CC(C)C1CCC(C)CC1OC(=O)C2=CC=CC=C2N

InChI

InChIKey=SOXAGEOHPCXXIO-UHFFFAOYSA-N

InChI=1S/C17H25NO2/c1-11(2)13-9-8-12(3)10-16(13)20-17(19)14-6-4-5-7-15(14)18/h4-7,11-13,16H,8-10,18H2,1-3H3

HIDE SMILES / InChI

Description
Sources: http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm079686.pdf
Curator's Comment: description was created based on several sources, including, http://www.skincancer.org/prevention/sun-protection/sunscreen/the-skin-cancer-foundations-guide-to-sunscreens

Menthyl anthranilate (meradimate) is an active ingredient used in sunscreen drug products for over-the-counter (OTC) human use. Maximum FDA-approved Concentration - 5%. Range of Protection - UVA2.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Sunburn 84 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9ae081af-4eac-4dbd-b2ac-48a2e80cb43d	Preventing		Approved 8429	MDSOLARSCIENCES SPF40 ULTRA-SPORT Approved Use Helps prevent sunburn. Higher SPF gives more sunburn protection. Retains SPF after 80 minutes of activity in the water or sweating

PubMed

PubMed

Title	Date	PubMed
Sunscreen use in photodermatoses.	2006 Jan	16311165

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Apply liberally 15 minutes before sun exposure. Reapply at least every 2 hours.

Route of Administration: Topical

In Vitro Use Guide

Unknown

Name

Type

Language

MERADIMATE

Official Name

English

CYCLOHEXANOL, 5-METHYL-2-(1-METHYLETHYL)-, 2-AMINOBENZOATE

Systematic Name

English

MERADIMATE [USAN]

Common Name

English

MENTHYL ANTHRANILATE [INCI]

Common Name

English

MENTHYL ANTHRANILATE [MI]

Common Name

English

MERADIMATE [MART.]

Common Name

English

meradimate [INN]

Common Name

English

MENTHYL ANTHRANILATE

Official Name

English

MERADIMATE [USP MONOGRAPH]

Common Name

English

ANTHRANILIC ACID, P-MENTH-3-YL ESTER

Common Name

English

Meradimate [WHO-DD]

Common Name

English

MERADIMATE [USP-RS]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C851

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

CFR

21 CFR 352.10

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

CFR

21 CFR 352.20

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

Code System Code Type Description

DRUG CENTRAL

4444

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

PRIMARY

ECHA (EC/EINECS)

205-129-8

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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USAN

LL-22

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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INN

7981

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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DAILYMED

J9QGD60OUZ

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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DRUG BANK

DB11096

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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RS_ITEM_NUM

1381742

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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EVMPD

SUB89716

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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ChEMBL

CHEMBL1597075

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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CAS

134-09-8

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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EPA CompTox

DTXSID3047895

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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RXCUI

91324

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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RxNorm

SMS_ID

300000027749

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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MERCK INDEX

m7178

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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Merck Index

WIKIPEDIA

MENTHYL ANTHRANILATE

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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FDA UNII

J9QGD60OUZ

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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PUBCHEM

8633

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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NCI_THESAURUS

C87223

Created by admin on Fri Dec 15 15:19:20 UTC 2023 , Edited by admin on Fri Dec 15 15:19:20 UTC 2023

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ACTIVE MOIETY


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