Details
Stereochemistry | ACHIRAL |
Molecular Formula | 3C7H5O3.Fe |
Molecular Weight | 467.183 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[Fe+3].OC1=CC=CC=C1C([O-])=O.OC2=CC=CC=C2C([O-])=O.OC3=CC=CC=C3C([O-])=O
InChI
InChIKey=ZRNHBOAYYNHVOY-UHFFFAOYSA-K
InChI=1S/3C7H6O3.Fe/c3*8-6-4-2-1-3-5(6)7(9)10;/h3*1-4,8H,(H,9,10);/q;;;+3/p-3
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/1137922
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1137922
Ferric (III) salicylate is a product, formed when iron (III) ions react with salicylates. The presence of ferric salicylate gives a solution a characteristic purple color, and is used for rapid determination of salicylic acid and its metabolites in plasma and urine.
Originator
Approval Year
PubMed
Title | Date | PubMed |
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Studies on the pharmacology of salicylates. | 1946 |
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Improved colorimetric determination of salicylic acid and its metabolites in urine. | 1975 Jul |
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Measurement of true salicylate concentrations in serum from patients with Reye's syndrome. | 1983 Jun |
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A rapid and simple color test for detection of salicylate in whole hemolyzed blood. | 1990 Jul-Aug |
Patents
Sample Use Guides
qualitative determination for the presence of salicylates was rapidly performed in the emergency department by adding a few drops of 10% ferric chloride (FeCl3) to 1 mL of urine. If salicylates are present, the solution changes to a brown/purple color. Positive results with the urine ferric chloride test only indicate that a salicylate is present; however, even very small amounts of a salicylate, such as a single ingested aspirin tablet, can give a positive test result. Most emergency departments no longer perform this test and instead obtain a plasma salicylate level because these results are now rapidly available from almost all hospital laboratories and are much more useful clinically.
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54686277
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30492-15-0
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J8QFJ59TK6
Created by
admin on Sat Dec 16 08:33:49 UTC 2023 , Edited by admin on Sat Dec 16 08:33:49 UTC 2023
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SUBSTANCE RECORD