DEPROSTIL

Details

Stereochemistry	UNKNOWN
Molecular Formula	C21H38O4
Molecular Weight	354.524
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCC(C)(O)CC[C@H]1CCC(=O)[C@@H]1CCCCCCC(O)=O

InChI

InChIKey=JERCJPRNXXOPNI-FYQIFJIOSA-N

InChI=1S/C21H38O4/c1-3-4-9-15-21(2,25)16-14-17-12-13-19(22)18(17)10-7-5-6-8-11-20(23)24/h17-18,25H,3-16H2,1-2H3,(H,23,24)/t17-,18-,21?/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4733330 | https://www.ncbi.nlm.nih.gov/pubmed/4414938 | https://www.ncbi.nlm.nih.gov/pubmed/4733332

Deprostil is prostaglandin E analog. The drug exhibits a prolonged inhibition of basal gastric acid secretion. Deprostil is the orally active anti-ulcer agent. It is a racemate with four possible optical isomers. Like deprostil the (nat)- and (epi)-isomers appear to be potentially useful therapeutic agents for the treatment of hypergastrlc acid secretion and peptic ulcers.

Approval Year

Sample Use Guides

In Vivo Use Guide

10-30 mg per kg

Route of Administration: Oral

Name

Type

Language

DEPROSTIL

Official Name

English

AY 22,469

Preferred Name

English

PROSTAN-1-OIC ACID, 15-HYDROXY-15-METHYL-9-OXO-

Common Name

English

(1R,2S)-2-(3-Hydroxy-3-methyloctyl)-5-oxocyclopentaneheptanoic acid

Systematic Name

English

AY-22469

Code

English

deprostil [INN]

Common Name

English

DEPROSTIL [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78568