EPITHIAZIDE SODIUM

Details

Stereochemistry	RACEMIC
Molecular Formula	C10H10ClF3N3O4S3.Na
Molecular Weight	447.837
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Na+].[NH-]S(=O)(=O)C1=C(Cl)C=C2NC(CSCC(F)(F)F)NS(=O)(=O)C2=C1

InChI

InChIKey=WXPHONCABYVYGC-UHFFFAOYSA-N

InChI=1S/C10H10ClF3N3O4S3.Na/c11-5-1-6-8(2-7(5)23(15,18)19)24(20,21)17-9(16-6)3-22-4-10(12,13)14;/h1-2,9,16-17H,3-4H2,(H-,15,18,19);/q-1;+1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14185229 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1872837/pdf/brmedj02517-0002.pdf

Epithiazide (epithizide) is a diuretic drug. Its combination with Veriloid under the trade name Thiaver was used in the 1960s for the treatment of hypertension.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Thiazide-sensitive sodium-chloride cotransporter 28 Target ID: CHEMBL1876 Sources: https://patents.google.com/patent/WO2014076235A1 \| https://www.ncbi.nlm.nih.gov/pubmed/14185229 \| https://books.google.ru/books?id=rmx2fLEdZvwC&pg=PA217&lpg=PA217&dq=EPITHIAZIDE retrieved from A Manual of Adverse Drug Interactions By J.P. Griffin, P.F. D'Arcy, p. 217	Inhibitor 8504

Name

Type

Language

2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE, 6-CHLORO-3,4-DIHYDRO-3-(((2,2,2-TRIFLUOROETHYL)THIO)METHYL)-, 1,1-DIOXIDE, MONOSODIUM SALT

Preferred Name

English

EPITHIAZIDE SODIUM

Common Name

English

2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE, 6-CHLORO-3,4-DIHYDRO-3-(((2,2,2-TRIFLUOROETHYL)THIO)METHYL)-, 1,1-DIOXIDE, SODIUM SALT (1:1)

Systematic Name

English

SODIUM, (6-CHLORO-3,4-DIHYDRO-7-SULFAMOYL-3-(((2,2,2-TRIFLUOROETHYL)THIO)METHYL)-2H-1,2,4-BENZOTHIADIAZIN-2-YL)-, 1,1-DIOXIDE

Common Name

English

EPITIZIDE SODIUM

Common Name

English

Code System Code Type Description

PUBCHEM

155801581

Created by admin on Mon Mar 31 23:45:47 GMT 2025 , Edited by admin on Mon Mar 31 23:45:47 GMT 2025

PRIMARY

PUBCHEM

FDA UNII

J5BF6H5XMP

Created by admin on Mon Mar 31 23:45:47 GMT 2025 , Edited by admin on Mon Mar 31 23:45:47 GMT 2025

PRIMARY

CAS

10083-13-3

Created by admin on Mon Mar 31 23:45:47 GMT 2025 , Edited by admin on Mon Mar 31 23:45:47 GMT 2025

PRIMARY

SUBSTANCE RECORD


					J5BF6H5XMP

EPITHIAZIDE SODIUM

Details

SMILES

InChI

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/14185229 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1872837/pdf/brmedj02517-0002.pdf

Approval Year

Targets

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/14185229 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1872837/pdf/brmedj02517-0002.pdf