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Details

Stereochemistry ACHIRAL
Molecular Formula C23H24O4
Molecular Weight 364.4343
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYCLOFENIL

SMILES

CC(=O)OC1=CC=C(C=C1)C(=C2CCCCC2)C3=CC=C(OC(C)=O)C=C3

InChI

InChIKey=GVOUFPWUYJWQSK-UHFFFAOYSA-N
InChI=1S/C23H24O4/c1-16(24)26-21-12-8-19(9-13-21)23(18-6-4-3-5-7-18)20-10-14-22(15-11-20)27-17(2)25/h8-15H,3-7H2,1-2H3

HIDE SMILES / InChI

Description

Cyclofenil is a anti-estrogen drug developed for the treatment of female infertility and for induction of ovulation. Cyclofenil exerts its action by binding to estrogen receptor beta and demonstrates agonism or antagonism depending on tissues type. The drug was withdrawn from the market due to high risk of hepatotoxicity.

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
9.4 nM [Kd]

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
SEXOVID

PubMed

Sample Use Guides

In Vivo Use Guide
600 mg/daily
Route of Administration: Oral
In Vitro Use Guide
Unknown