U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1'',3A-DI-EPI-PERINDOPRIL, (1''R,3AR)-

SMILES

CCC[C@@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@@H]2C[C@H]1C(O)=O)C(=O)OCC

InChI

InChIKey=IPVQLZZIHOAWMC-OTJKEOIZSA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13+,14+,15-,16-/m0/s1

HIDE SMILES / InChI

Description

(1''R,3AR)-1'',3A-di-epi-Perindopril is an epimer (S, RS, SR) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This form of the drug is much less active than the parent compound, perindopril.

Approval Year

Unknown
149124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
1H-INDOLE-2-CARBOXYLIC ACID, 1-(2-((1-(ETHOXYCARBONYL)BUTYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S-(1(R*(S*)),2.ALPHA.,3A.ALPHA.,7A.BETA.))-
Preferred Name English
1'',3A-DI-EPI-PERINDOPRIL, (1''R,3AR)-
Common Name English
Code System Code Type Description
PUBCHEM
9533936
Created by admin on Mon Mar 31 23:24:02 GMT 2025 , Edited by admin on Mon Mar 31 23:24:02 GMT 2025
PRIMARY
CAS
145513-94-6
Created by admin on Mon Mar 31 23:24:02 GMT 2025 , Edited by admin on Mon Mar 31 23:24:02 GMT 2025
PRIMARY
FDA UNII
J3VG2W26WZ
Created by admin on Mon Mar 31 23:24:02 GMT 2025 , Edited by admin on Mon Mar 31 23:24:02 GMT 2025
PRIMARY
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966