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Details

Stereochemistry ABSOLUTE
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1'',3A-DI-EPI-PERINDOPRIL, (1''R,3AR)-

SMILES

[H][C@@]12C[C@H](N(C(=O)[C@H](C)N[C@H](CCC)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O

InChI

InChIKey=IPVQLZZIHOAWMC-OTJKEOIZSA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13+,14+,15-,16-/m0/s1

HIDE SMILES / InChI

Description

(1''R,3AR)-1'',3A-di-epi-Perindopril is an epimer (S, RS, SR) of the drug perindopril which is commonly used to treat high blood pressure, hypertension, heart failure, or stable coronary artery disease. This form of the drug is much less active than the parent compound, perindopril.

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
1'',3A-DI-EPI-PERINDOPRIL, (1''R,3AR)-
Common Name English
1H-INDOLE-2-CARBOXYLIC ACID, 1-(2-((1-(ETHOXYCARBONYL)BUTYL)AMINO)-1-OXOPROPYL)OCTAHYDRO-, (2S-(1(R*(S*)),2.ALPHA.,3A.ALPHA.,7A.BETA.))-
Systematic Name English
Code System Code Type Description
PUBCHEM
9533936
Created by admin on Sat Dec 16 10:41:55 GMT 2023 , Edited by admin on Sat Dec 16 10:41:55 GMT 2023
PRIMARY
CAS
145513-94-6
Created by admin on Sat Dec 16 10:41:55 GMT 2023 , Edited by admin on Sat Dec 16 10:41:55 GMT 2023
PRIMARY
FDA UNII
J3VG2W26WZ
Created by admin on Sat Dec 16 10:41:55 GMT 2023 , Edited by admin on Sat Dec 16 10:41:55 GMT 2023
PRIMARY
NIH
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