Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C14H22N6O5.ClH |
Molecular Weight | 390.823 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(C)[C@H](N)C(=O)OC[C@H](CO)OCN1C=NC2=C1N=C(N)NC2=O
InChI
InChIKey=ZORWARFPXPVJLW-OZZZDHQUSA-N
InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H/t8-,9-;/m0./s1
Originator
Approval Year
PubMed
Title | Date | PubMed |
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Cytomegalovirus infection in immunocompetent and immunocompromised individuals--a review. | 2001 Aug |
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Cytomegalovirus infection: the point in 2001. | 2001 Oct |
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Valganciclovir: A new oral alternative for cytomegalovirus retinitis in human immunodeficiency virus-seropositive individuals. | 2002 Sep |
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Valganciclovir: a new treatment for cytomegalovirus retinitis. | 2002 Winter |
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Cytomegalovirus prophylaxis with valganciclovir in kidney, pancreas-kidney, and pancreas transplantation. | 2004 Aug |
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Valganciclovir for the prevention and treatment of cytomegalovirus disease in immunocompromised hosts. | 2004 Feb |
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A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein. | 2004 Mar-Apr |
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Valganciclovir for the prophylaxis of cytomegalovirus disease in pediatric liver transplant recipients. | 2004 May 15 |
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Pre-emptive treatment with oral valganciclovir in management of CMV infection after cardiac transplantation. | 2004 Nov |
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Cytomegalovirus retinitis in a patient treated with anti-tumor necrosis factor alpha antibody therapy for rheumatoid arthritis. | 2004 Nov 1 |
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Valganciclovir prophylaxis in patients at high risk for the development of cytomegalovirus disease. | 2004 Sep |
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Cytomegalovirus retinitis in an immunocompetent patient. | 2005 Apr |
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Pharmacokinetics of antiviral agents for the treatment of cytomegalovirus infection. | 2005 Apr 15 |
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[Valganciclovir maintenance therapy in AIDS: treatment failure due to the development of cytomegalovirus resistance to ganciclovir]. | 2005 Feb |
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Initial experience with oral valganciclovir for pre-emptive cytomegalovirus therapy after lung transplantation. | 2005 Jul |
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Cytomegalovirus colitis mimicking ischemic colitis in an immunocompetent host. | 2005 Jul-Aug |
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Successful treatment of mediastinal lymphomatoid granulomatosis with rituximab monotherapy. | 2005 Mar |
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Clinical utility of cytomegalovirus (CMV) serology testing in high-risk CMV D+/R- transplant recipients. | 2005 May |
Patents
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Common Name | English |
Code System | Code | Type | Description | ||
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DTXSID40170034
Created by
admin on Fri Dec 15 15:57:45 GMT 2023 , Edited by admin on Fri Dec 15 15:57:45 GMT 2023
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135565147
Created by
admin on Fri Dec 15 15:57:45 GMT 2023 , Edited by admin on Fri Dec 15 15:57:45 GMT 2023
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175865-61-9
Created by
admin on Fri Dec 15 15:57:45 GMT 2023 , Edited by admin on Fri Dec 15 15:57:45 GMT 2023
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J0IEW0BSHV
Created by
admin on Fri Dec 15 15:57:45 GMT 2023 , Edited by admin on Fri Dec 15 15:57:45 GMT 2023
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PRIMARY |
PARENT (SALT/SOLVATE)
SUBSTANCE RECORD