U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C9H19NO
Molecular Weight 157.2533
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,2,6,6-TETRAMETHYL-4-PIPERIDINOL

SMILES

CC1(C)CC(O)CC(C)(C)N1

InChI

InChIKey=VDVUCLWJZJHFAV-UHFFFAOYSA-N
InChI=1S/C9H19NO/c1-8(2)5-7(11)6-9(3,4)10-8/h7,10-11H,5-6H2,1-4H3

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
A novel analytical method to evaluate directly catalase activity of microorganisms and mammalian cells by ESR oximetry.
2010-09
Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes.
2010-08
Nucleoprotein Diet Ameliorates Arthritis Symptoms in Mice Transgenic for Human T-Cell Leukemia Virus Type I (HTLV-1).
2010-03
Endogenous reactive oxygen species are essential for proliferation of neural stem/progenitor cells.
2009-10-20
NADPH oxidase-derived reactive oxygen species in skeletal muscle modulates the exercise pressor reflex.
2009-08
Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase.
2009-07-01
Superoxide dismutase analog (Tempol: 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine 1-oxyl) treatment restores erectile function in diabetes-induced impotence.
2009-06-26
Spin scavenging analysis of myoglobin protein-centered radicals using stable nitroxide radicals: characterization of oxoammonium cation-induced modifications.
2009-06
Iodixanol, constriction of medullary descending vasa recta, and risk for contrast medium-induced nephropathy.
2009-06
An in vitro screening cascade to identify neuroprotective antioxidants in ALS.
2009-04-15
Singlet oxygen scavenging activity and cytotoxicity of essential oils from rutaceae.
2008-07
4-Hydr-oxy-2,2,6,6-tetra-methyl-piperidinium trichloro-acetate.
2008-02-29
4-Hydr-oxy-2,2,6,6-tetra-methyl-piperidinium chloride-hydroxonium chloride (3/1).
2008-01-25
4-Hydroxy-2,2,6,6-tetra-methyl-piperidinium trifluoro-acetate.
2007-12-18
The role of reactive oxygen species in capsaicin-induced mechanical hyperalgesia and in the activities of dorsal horn neurons.
2007-12-15
Photochemical properties of camptothecin in the presence of copper(II) ions: the role of radicals as prospective species in photodynamic therapy.
2007-09
Measurement and characterization of singlet oxygen production in copper ion-catalyzed aerobic oxidation of ascorbic acid.
2007-04-15
Electron spin resonance studies on the oxidation mechanism of sterically hindered cyclic amines in TiO2 photocatalytic systems.
2006-07-06
Endothelin(B) receptor blocker inhibits high glucose-induced synthesis of fibronectin in human peritoneal mesothelial cells.
2006-05-26
Chronic intermittent hypoxia alters NE reactivity and mechanics of skeletal muscle resistance arteries.
2006-04
Reduced nitric oxide bioavailability contributes to skeletal muscle microvessel rarefaction in the metabolic syndrome.
2005-08
Oxidant stress and constrictor reactivity impair cerebral artery dilation in obese Zucker rats.
2005-02
Angiotensin-induced defects in renal oxygenation: role of oxidative stress.
2005-01
Central Tempol alters basal sympathetic nerve discharge and attenuates sympathetic excitation to central ANG II.
2004-12
Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries.
2004-08
The role of reactive oxygen species in microcystin-LR-induced DNA damage.
2004-07-15
NaCl transport across the opercular epithelium of Fundulus heteroclitus is inhibited by an endothelin to NO, superoxide, and prostanoid signaling axis.
2004-03
Vascular effects of singlet oxygen (1O2) generated by photo-excitation on adrenergic neurotransmission in isolated rabbit mesenteric vein.
2002
Inhibition of Ca2+-induced relaxation by oxidized tungsten wires and paratungstate.
2001-10
Patents
Name Type Language
NSC-16575
Preferred Name English
2,2,6,6-TETRAMETHYL-4-PIPERIDINOL
Systematic Name English
4-PIPERIDINOL, 2,2,6,6-TETRAMETHYL-
Systematic Name English
2,2,6,6-TETRAMETHYL-4-HYDROXYPIPERIDINE
Systematic Name English
LASTAR A
Common Name English
4-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDINE
Systematic Name English
4-HYDROXYL-2,2,6,6-TETRAMETHYL PIPERIDINE
Systematic Name English
Code System Code Type Description
NSC
16575
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY
PUBCHEM
75471
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY
ECHA (EC/EINECS)
219-291-2
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY
MESH
C024330
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY
EPA CompTox
DTXSID3029655
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY
CAS
2403-88-5
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY
FDA UNII
IS23Q8EGZ6
Created by admin on Mon Mar 31 18:53:40 GMT 2025 , Edited by admin on Mon Mar 31 18:53:40 GMT 2025
PRIMARY