PRAZOCILLIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H18Cl2N4O4S
Molecular Weight	469.342
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C3=C(C)C=NN3C4=C(Cl)C=CC=C4Cl)C(O)=O

InChI

InChIKey=XRCKXULNIUSXFZ-HYSWKAIVSA-N

InChI=1S/C19H18Cl2N4O4S/c1-8-7-22-25(13-9(20)5-4-6-10(13)21)12(8)15(26)23-11-16(27)24-14(18(28)29)19(2,3)30-17(11)24/h4-7,11,14,17H,1-3H3,(H,23,26)(H,28,29)/t11-,14+,17-/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/5142734 | https://www.ncbi.nlm.nih.gov/pubmed/5004081 | https://www.ncbi.nlm.nih.gov/pubmed/4992224

Prazocillin is 6-aminopenicillanic acid derivative patented by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt. as a bactericidal compound. The activity of Prazocillin against Staphylococcus aureus strains was the same as that of dikloxacillin, but Prazocillin was more active against Bacillus subtilis ATCC 6633. Prazocillin had a bactericidal effect on a penicillin-resistant S. aureus strain at concentrations of 1 μg/ml. Pyrazocillin inhibits bacterial penicillinase in vitro.

Originator

Approval Year

PubMed

Title	Date	PubMed

Patents

Name

Type

Language

PRAZOCILLIN

Official Name

English

prazocillin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1500