Details
Stereochemistry | ACHIRAL |
Molecular Formula | C22H25NO2 |
Molecular Weight | 335.4394 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCCN1C=C(C(=O)CC2=C(OC)C=CC=C2)C3=C1C=CC=C3
InChI
InChIKey=FFLSJIQJQKDDCM-UHFFFAOYSA-N
InChI=1S/C22H25NO2/c1-3-4-9-14-23-16-19(18-11-6-7-12-20(18)23)21(24)15-17-10-5-8-13-22(17)25-2/h5-8,10-13,16H,3-4,9,14-15H2,1-2H3
JWH-250 or (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family that acts as a cannabinoid agonist at both the CB1 and CB2 receptors, with a Ki of 11 nM at CB1 and 33 nM at CB2. JWH-250 does not have any therapeutic application, however it is found in many herbal products that are smoked for their psychoactive effects. JWH-250 is a controlled substance by FDA.
CNS Activity
Originator
Approval Year
Sample Use Guides
Synthetic cannabioids such as JWH-250 are usually smoked by wrapping it in joints, smoking it in pipes, or inhaling fumes via vaporizers.
Route of Administration:
Respiratory
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27260125
Hippocampal neurons were treated with 1 and 10 uM of JWH-250 to test its effect on on Ca2+ spiking. JWH-250 was shown to be a full agonist of neuronal cannabinoid receptors with pEC50 value of 6.8 (cAMP assay).
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WIKIPEDIA |
Designer-drugs-JWH-250
Created by
admin on Sat Dec 16 08:32:56 GMT 2023 , Edited by admin on Sat Dec 16 08:32:56 GMT 2023
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DEA NO. |
6250
Created by
admin on Sat Dec 16 08:32:56 GMT 2023 , Edited by admin on Sat Dec 16 08:32:56 GMT 2023
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IP9911R8A0
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DTXSID40235556
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44397540
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admin on Sat Dec 16 08:32:56 GMT 2023 , Edited by admin on Sat Dec 16 08:32:56 GMT 2023
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JWH-250
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admin on Sat Dec 16 08:32:56 GMT 2023 , Edited by admin on Sat Dec 16 08:32:56 GMT 2023
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864445-43-2
Created by
admin on Sat Dec 16 08:32:56 GMT 2023 , Edited by admin on Sat Dec 16 08:32:56 GMT 2023
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ACTIVE MOIETY