P-COUMARIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H8O3
Molecular Weight	164.158
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

SMILES

OC(=O)\C=C\C1=CC=C(O)C=C1

InChI

InChIKey=NGSWKAQJJWESNS-ZZXKWVIFSA-N

InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary Target	Pharmacology	Potency
Hydroxycarboxylic acid receptor 2 32	Agonist 2,678	310.0 µM [EC50]
Estrogen receptor beta 110	Agonist 2,678	4.89 µM [EC50]
Aldose reductase 44	Inhibitor 8,297
Carbonic anhydrase II 88	Inhibitor 8,297	0.98 µM [Ki]
Carbonic anhydrase I 62	Inhibitor 8,297	1.07 µM [Ki]
Carbonic anhydrase VII 34	Inhibitor 8,297	5.23 µM [Ki]
Carbonic anhydrase IX 35	Inhibitor 8,297	5.33 µM [Ki]

PubMed

Show entries

Title	Date	PubMed
Impaired mitochondrial pyruvate importation in a patient and a fetus at risk.	2003 Mar	12649063
Antioxidant and antigenotoxic effects of plant cell wall hydroxycinnamic acids in cultured HT-29 cells.	2005 Jun	15841493
A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase.	2005 Mar	15740983
Antitubercular sterols from Thalia multiflora Horkel ex Koernicke.	2005 Oct	16261518
Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.	2006 May	16308312

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Name

Type

Language

P-COUMARIC ACID

Common Name

English

P-coumaric acid [WHO-DD]

Common Name

English

P-COUMARIC ACID [MI]

Common Name

English

NSC-674321

Code

English

NSC-59260

Code

English

Showing 1 to 5 of 23 entries

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Code System

Code

Type

Description

CHEBI

32374

PRIMARY

FDA UNII

IBS9D1EU3J

PRIMARY

SMS_ID

100000089731

PRIMARY

CAS

501-98-4

PRIMARY

CAS

7400-08-0

NON-SPECIFIC STEREOCHEMISTRY

Showing 1 to 5 of 18 entries

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SUBSTANCE RECORD


					IBS9D1EU3J

P-COUMARIC ACID

SMILES

InChI

Approval Year

Targets

PubMed

Patents