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Details

Stereochemistry ACHIRAL
Molecular Formula C12H13F3N2O2
Molecular Weight 274.239
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUZINAMIDE

SMILES

CNC(=O)N1CC(C1)OC2=CC=CC(=C2)C(F)(F)F

InChI

InChIKey=YULWJRNIKFFGNU-UHFFFAOYSA-N
InChI=1S/C12H13F3N2O2/c1-16-11(18)17-6-10(7-17)19-9-4-2-3-8(5-9)12(13,14)15/h2-5,10H,6-7H2,1H3,(H,16,18)

HIDE SMILES / InChI
Fluzinamide (AHR-8559), an anticonvulsant agent that was studied in patients with refractory partial seizures. However, information about the further development of this drug is not available.

Approval Year

PubMed

PubMed

TitleDatePubMed
Anticonvulsant action of fluzinamide (AHR-8559) on kindled amygdaloid seizures.
1984 Aug
Simultaneous determination of fluzinamide and three of its active metabolites in plasma by high-performance liquid chromatography.
1984 Dec 12
Pilot study of fluzinamide (N-methyl-3-[3-(trifluoromethyl)phenoxy]-1-azetidinecarboxamide) in refractory partial seizures.
1985 Aug
Pharmacokinetic and dose tolerability study of ADD 94057 in comedicated patients with partial seizures.
1992 Jan-Feb
Patents

Patents

Name Type Language
FLUZINAMIDE
INN   USAN  
INN   USAN  
Official Name English
fluzinamide [INN]
Common Name English
1-AZETIDINECARBOXAMIDE, N-METHYL-3-(3-(TRIFLUOROMETHYL)PHENOXY)-
Systematic Name English
AHR-8559
Code English
FLUZINAMIDE [USAN]
Common Name English
N-METHYL-3-((.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)OXY)-1-AZETIDINECARBOXAMIDE
Systematic Name English
Code System Code Type Description
FDA UNII
IAF7F741SX
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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INN
5385
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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PUBCHEM
53467
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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EVMPD
SUB07770MIG
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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ChEMBL
CHEMBL2107449
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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NCI_THESAURUS
C169999
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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SMS_ID
100000080408
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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EPA CompTox
DTXSID90227123
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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CAS
76263-13-3
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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MESH
C042116
Created by admin on Fri Dec 15 17:25:12 GMT 2023 , Edited by admin on Fri Dec 15 17:25:12 GMT 2023
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