BICUCULLINE METHOCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H20NO6.Cl
Molecular Weight	417.84
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Cl-].[H][C@]1(OC(=O)C2=C3OCOC3=CC=C12)[C@]4([H])C5=CC6=C(OCO6)C=C5CC[N+]4(C)C

InChI

InChIKey=RLJKFAMYSYWMND-GRTNUQQKSA-M

InChI=1S/C21H20NO6.ClH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
GABA-A receptor; anion channel 202 Target ID: CHEMBL1907607 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3027337 \| https://www.ncbi.nlm.nih.gov/pubmed/3000559	Antagonist 2778		38.0 µM [Ki]
Small conductance calcium-activated potassium channel protein 3 3 Target ID: CHEMBL3780 Sources: https://www.ncbi.nlm.nih.gov/pubmed/18998663	Inhibitor 8297		7.0 µM [IC50]

Name

Type

Language

BICUCULLINE METHOCHLORIDE

Common Name

English

1,3-DIOXOLO(4,5-G)ISOQUINOLINIUM, 5-(6,8-DIHYDRO-8-OXOFURO(3,4-E)-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-, CHLORIDE, (R-(R*,S*))-

Common Name

English

Code System Code Type Description

CAS

38641-83-7