Details
Stereochemistry | RACEMIC |
Molecular Formula | C19H18ClN3O3 |
Molecular Weight | 371.818 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)C(=O)OC1N=C(C2=CC=CC=C2)C3=C(C=CC(Cl)=C3)N(C)C1=O
InChI
InChIKey=PXBVEXGRHZFEOF-UHFFFAOYSA-N
InChI=1S/C19H18ClN3O3/c1-22(2)19(25)26-17-18(24)23(3)15-10-9-13(20)11-14(15)16(21-17)12-7-5-4-6-8-12/h4-11,17H,1-3H3
Camazepam is a benzodiazepine psychoactive drug, marketed under the brand names Albego, Limpidon and Paxor. It is the dimethyl carbamate ester of temazepam, a metabolite of diazepam. While it possesses anxiolytic, anticonvulsant, skeletal muscle relaxant and hypnotic properties it differs from other benzodiazepines in that its anxiolytic properties are particularly prominent but has comparatively limited anticonvulsant, hypnotic and skeletal muscle relaxant properties. Changes in sleep with camazepam were minimal. However, non-anxious subjects reported being more relaxed the next day. Camazepam may cause skin disorders.
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Screening, library-assisted identification and validated quantification of 23 benzodiazepines, flumazenil, zaleplone, zolpidem and zopiclone in plasma by liquid chromatography/mass spectrometry with atmospheric pressure chemical ionization. | 2004 Aug |
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Development and validation of an EI-GC-MS method for the determination of benzodiazepine drugs and their metabolites in blood: applications in clinical and forensic toxicology. | 2010 Aug 1 |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6120717
10, 20 and 40 mg overnight
Route of Administration:
Oral
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Classification Tree | Code System | Code | ||
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DEA NO. |
2749
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WHO-ATC |
N05BA15
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NCI_THESAURUS |
C1012
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WHO-VATC |
QN05BA15
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469
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HZ3XRH03C3
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3500
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SUB06061MIG
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100000081596
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CAMAZEPAM
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DB01489
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DTXSID50865803
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252-866-6
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C98123
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m2997
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C084596
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CHEMBL1095282
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ACTIVE MOIETY