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Details

Stereochemistry UNKNOWN
Molecular Formula C17H22N2O2
Molecular Weight 286.3688
Optical Activity ( - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FENPIPALONE, (-)-

SMILES

CN1CC(CCN2CCC(=CC2)C3=CC=CC=C3)OC1=O

InChI

InChIKey=YUORBURTMIUPMW-UHFFFAOYSA-N
InChI=1S/C17H22N2O2/c1-18-13-16(21-17(18)20)9-12-19-10-7-15(8-11-19)14-5-3-2-4-6-14/h2-7,16H,8-13H2,1H3

HIDE SMILES / InChI

Description

FENPIPALONE is an oxazolidinone derivative with central nervous system depressant and antiinflammatory activity in animal models. However, FENPIPALONE did not demonstrate any usefulness for severely ill chronic schizophrenic patients.

CNS Activity

CNS Active
3913
Curator's Comment: Known to be CNS active in mouse and probably not active in human.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
Two pilot studies of AHR-1680 in chronic schizophrenic patients.
1969 May-Jun
5-(2-Aminoethyl)-2-oxazolidinones with central nervous system depressant and antiinflammatory activity.
1973 Oct
Name Type Language
FENPIPALONE, (-)-
Common Name English
2-OXAZOLIDINONE, 5-(2-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)ETHYL)-3-METHYL-, (-)-
Systematic Name English
Code System Code Type Description
CAS
55121-38-5
Created by admin on Sat Dec 16 10:27:23 GMT 2023 , Edited by admin on Sat Dec 16 10:27:23 GMT 2023
PRIMARY
FDA UNII
HVM95TFZ7Q
Created by admin on Sat Dec 16 10:27:23 GMT 2023 , Edited by admin on Sat Dec 16 10:27:23 GMT 2023
PRIMARY
SUBSTANCE RECORD
Structure of FENPIPALONE, (-)-
NIH
NCATS
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