RJR-2429 dihydrochloride

Cl.Cl.C1CN2CCC1CC2C3=CN=CC=C3

InChIKey=PIUNXHHZRIUBOV-UHFFFAOYSA-N

InChI=1S/C12H16N2.2ClH/c1-2-11(9-13-5-1)12-8-10-3-6-14(12)7-4-10;;/h1-2,5,9-10,12H,3-4,6-8H2;2*1H

Targets

Primary Target	Pharmacology	Condition	Potency
Nicotinic acetylcholine receptor alpha-4/beta-2 5 Target ID: CHEMBL3301382 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20114055	Agonist 2752		0.46 nM [Ki]
Neuronal acetylcholine receptor subunit alpha-7 14 Target ID: P49582 Gene ID: 11441.0 Gene Symbol: Chrna7 Target Organism: Mus musculus (Mouse) Sources: https://www.ncbi.nlm.nih.gov/pubmed/20114055	Agonist 2752		7.6 nM [Ki]

Name

Type

Language

RJR-2429 dihydrochloride

Common Name

English

(±)-2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane dihydrochloride

Preferred Name

English

2-(3-Pyridinyl)-1-azabicyclo[2.2.2]octane dihydrochloride

Systematic Name

English

1-Azabicyclo[2.2.2]octane, 2-(3-pyridinyl)-, hydrochloride (1:2)

Systematic Name

English

Code System Code Type Description

CAS

1021418-53-0

Created by admin on Wed Apr 02 16:29:48 GMT 2025 , Edited by admin on Wed Apr 02 16:29:48 GMT 2025

PRIMARY

FDA UNII

HR2U7BXS5G

Created by admin on Wed Apr 02 16:29:48 GMT 2025 , Edited by admin on Wed Apr 02 16:29:48 GMT 2025

PRIMARY

PUBCHEM

56972204

Created by admin on Wed Apr 02 16:29:48 GMT 2025 , Edited by admin on Wed Apr 02 16:29:48 GMT 2025

PRIMARY

PARENT (SALT/SOLVATE)


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RJR-2429

SUBSTANCE RECORD


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