Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C24H31N3O |
| Molecular Weight | 377.5224 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(CC1=CC=CC=C1)N(C)CC2=C(C(C)C)C(=O)N(N2C)C3=CC=CC=C3
InChI
InChIKey=GNUXVOXXWGNPIV-UHFFFAOYSA-N
InChI=1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3
Famprofazone, a nonsteroidal anti-inflammatory agent, is found in a multi-ingredient medication (Gewodin) used for pain relief. It is available over-the-counter in Taiwan. Famprofazone transforms to methamphetamine (MA) and amphetamine (AM) following administration, which is responsible for the side effects of the drug. For example, famprofazone user might be interpreted as an illicit MA abuser in Taiwan because the user's urine tested positive for MA.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Toxicokinetics of amphetamines: metabolism and toxicokinetic data of designer drugs, amphetamine, methamphetamine, and their N-alkyl derivatives. | 2002 Apr |
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| Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results. | 2002 May |
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| Metabolic profile of amphetamine and methamphetamine following administration of the drug famprofazone. | 2003 Oct |
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| Famprofazone as the source of methamphetamine and amphetamine in urine specimen collected during sport competition. | 2007 Mar |
Patents
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NCI_THESAURUS |
C257
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245-284-9
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1130
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759244
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22881-35-2
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Famprofazone
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HN0NCX453C
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DTXSID3045435
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C65616
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3326
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C076013
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CHEMBL1475693
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SUB07506MIG
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100000081760
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2645
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ACTIVE MOIETY
