Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H15NO4S2 |
| Molecular Weight | 421.489 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC(=O)C1=CC=C(C=C1)C2=CC=C(O2)\C=C3/SC(=S)N(CC4=CC=CC=C4)C3=O
InChI
InChIKey=AEZGRQSLKVNPCI-UNOMPAQXSA-N
InChI=1S/C22H15NO4S2/c24-20-19(29-22(28)23(20)13-14-4-2-1-3-5-14)12-17-10-11-18(27-17)15-6-8-16(9-7-15)21(25)26/h1-12H,13H2,(H,25,26)/b19-12-
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
2869 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg single, oral dose: 30 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: FEMALE food status: FASTED |
|
1716 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg single, oral dose: 30 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
1900 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg 1 times / day multiple, oral dose: 30 mg/kg route of administration: Oral experiment type: MULTIPLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
2594 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
100 mg/kg single, oral dose: 100 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
1800 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
100 mg/kg 1 times / day multiple, oral dose: 100 mg/kg route of administration: Oral experiment type: MULTIPLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
15248 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg single, oral dose: 30 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: FEMALE food status: FASTED |
|
6950 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg single, oral dose: 30 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
8206 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg 1 times / day multiple, oral dose: 30 mg/kg route of administration: Oral experiment type: MULTIPLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
13962 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
100 mg/kg single, oral dose: 100 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
9840 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
100 mg/kg 1 times / day multiple, oral dose: 100 mg/kg route of administration: Oral experiment type: MULTIPLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
3.84 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg single, oral dose: 30 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: FEMALE food status: FASTED |
|
4.68 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg single, oral dose: 30 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
9.54 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
30 mg/kg 1 times / day multiple, oral dose: 30 mg/kg route of administration: Oral experiment type: MULTIPLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
3.95 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
100 mg/kg single, oral dose: 100 mg/kg route of administration: Oral experiment type: SINGLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
|
3.48 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/31270275/ |
100 mg/kg 1 times / day multiple, oral dose: 100 mg/kg route of administration: Oral experiment type: MULTIPLE co-administered: |
LEUKADHERIN-1 plasma | Rattus norvegicus population: HEALTHY age: ADULT sex: MALE food status: FASTED |
| Name | Type | Language | ||
|---|---|---|---|---|
|
Code | English | ||
|
Preferred Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
2055362-72-4
Created by
admin on Wed Apr 02 01:44:08 GMT 2025 , Edited by admin on Wed Apr 02 01:44:08 GMT 2025
|
PRIMARY | |||
|
5342077
Created by
admin on Wed Apr 02 01:44:08 GMT 2025 , Edited by admin on Wed Apr 02 01:44:08 GMT 2025
|
PRIMARY | |||
|
HF23I3UYO2
Created by
admin on Wed Apr 02 01:44:08 GMT 2025 , Edited by admin on Wed Apr 02 01:44:08 GMT 2025
|
PRIMARY |
ACTIVE MOIETY
SALT/SOLVATE (PARENT)
