BIS(MALTOLATO)OXOVANADIUM

O=[V++].CC1=C([O-])C(=O)C=CO1.CC2=C([O-])C(=O)C=CO2

InChIKey=XUOLEICXAPEOSI-UHFFFAOYSA-L

InChI=1S/2C6H6O3.O.V/c2*1-4-6(8)5(7)2-3-9-4;;/h2*2-3,8H,1H3;;/q;;;+2/p-2

Targets

Primary Target	Pharmacology	Condition	Potency
Tyrosine-protein phosphatase non-receptor type 1 4 Target ID: P18031 Gene ID: 5770.0 Gene Symbol: PTPN1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/18728000 \| https://www.ncbi.nlm.nih.gov/pubmed/12888267	Inhibitor 8297		0.86 µM [IC50]

PubMed

Title	Date	PubMed
Effect of vanadium on insulin sensitivity and appetite.	2001 Jun	11398143
Vanadium increases GLUT4 in diabetic rat skeletal muscle.	2002 Apr	12083368
Mechanisms by which bis(maltolato)oxovanadium(IV) normalizes phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression in streptozotocin-diabetic rats in vivo.	2002 Dec	12446591
Bis(maltolato)oxovanadium(IV) inhibits the activity of PTP1B in Zucker rat skeletal muscle in vivo.	2002 Jan	11936837
Effects of bis(alpha-furancarboxylato)oxovanadium(IV) on glucose metabolism in fat-fed/streptozotocin-diabetic rats.	2007 Oct 31	17651728
Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis.	2007 Sep	17696279
Effect of bis (maltolato) oxovanadium (BMOV) in uric acid and sodium arsenite-induced vascular endothelial dysfunction in rats.	2008 Aug 29	17658639
Exposure to bis(maltolato)oxovanadium(IV) increases levels of hepcidin mRNA and impairs the homeostasis of iron but not that of manganese.	2014 Nov	25168077

Name

Type

Language

BIS(MALTOLATO)OXOVANADIUM

Common Name

English

VO(MA)2

Common Name

English

BMOV

Common Name

English

BIS((2-METHYL-4-OXO-PYRAN-3-YL)OXY)-OXO-VANADIUM

Systematic Name

English

VANADIUM, BIS(3-HYDROXY-2-METHYL-4H-PYRAN-4-ONATO-O3,O4)OXO-, (SP-5-31)-

Systematic Name

English

Code System Code Type Description

EPA CompTox

DTXSID50191593