SUDEXANOX

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C21H23NO5S
Molecular Weight	401.476
Optical Activity	( + / - )
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SUDEXANOX

Structure Search

SMILES

CCCCCCC1=CC(=CC2=C1OC3=CC=C(C=C3C2=O)C(O)=O)S(C)(=N)=O

InChI

InChIKey=DIGXMFZQXQUVMR-UHFFFAOYSA-N

InChI=1S/C21H23NO5S/c1-3-4-5-6-7-13-10-15(28(2,22)26)12-17-19(23)16-11-14(21(24)25)8-9-18(16)27-20(13)17/h8-12,22H,3-7H2,1-2H3,(H,24,25)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/2897466 | https://www.ncbi.nlm.nih.gov/pubmed/3760070 | https://www.ncbi.nlm.nih.gov/pubmed/430479

Sudexanox is a xanthone derivative patented by French pharmaceutical company Roussel-UCLAF for the treatment of allergy, allergic asthma, and asthmatic bronchitis. In preclinical studies, Sudexanox possesses potent activity in the IgE-induced rat passive cutaneous anaphylaxis model.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
High-performance liquid chromatographic method for the determination of sudexanox as the free acid in plasma.	1986 Aug 2	3760070

Patents

Patents

Name

Type

Language

SUDEXANOX

Official Name

English

sudexanox [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29712

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Code System Code Type Description

SMS_ID

100000083233

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PUBCHEM

68785

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ChEMBL

CHEMBL1627264

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EVMPD

SUB10668MIG

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MESH

C050424

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FDA UNII

H6C0F5AD7D

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EPA CompTox

DTXSID80866707

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NCI_THESAURUS

C75144

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INN

4839

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CAS

58761-87-8

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ACTIVE MOIETY


					H6C0F5AD7D

SUDEXANOX