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Details

Stereochemistry ABSOLUTE
Molecular Formula C14H18N2O3
Molecular Weight 262.3043
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PHYSOVENINE

SMILES

[H][C@]12OCC[C@@]1(C)C3=CC(OC(=O)NC)=CC=C3N2C

InChI

InChIKey=LXTKNVLLWOLCOV-JSGCOSHPSA-N
InChI=1S/C14H18N2O3/c1-14-6-7-18-12(14)16(3)11-5-4-9(8-10(11)14)19-13(17)15-2/h4-5,8,12H,6-7H2,1-3H3,(H,15,17)/t12-,14-/m0/s1

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Efficient formal total synthesis of physostigmine and physovenine: conformational analysis of key intermediates.
2002 Feb
Novel anticholinesterases based on the molecular skeletons of furobenzofuran and methanobenzodioxepine.
2005 Feb 24
An interrupted Fischer indolization approach toward fused indoline-containing natural products.
2009 Aug 6
Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions.
2009 Jan 1
Patents
Name Type Language
PHYSOVENINE
MI  
Common Name English
2H-FURO(2,3-B)INDOL-5-OL, 3,3A,8,8A-TETRAHYDRO-3A,8-DIMETHYL-, METHYLCARBAMATE (ESTER), (3AS-CIS)-
Systematic Name English
2H-FURO(2,3-B)INDOL-5-OL, 3,3A,8,8A-TETRAHYDRO-3A,8-DIMETHYL-, 2-(N-METHYLCARBAMATE), (3AS,8AS)-
Systematic Name English
(-)-PHYSOVENINE
Common Name English
PHYSOVENINE [MI]
Common Name English
Code System Code Type Description
PUBCHEM
442113
Created by admin on Sat Dec 16 08:02:31 GMT 2023 , Edited by admin on Sat Dec 16 08:02:31 GMT 2023
PRIMARY
FDA UNII
H67Q5553UW
Created by admin on Sat Dec 16 08:02:31 GMT 2023 , Edited by admin on Sat Dec 16 08:02:31 GMT 2023
PRIMARY
EPA CompTox
DTXSID90877566
Created by admin on Sat Dec 16 08:02:31 GMT 2023 , Edited by admin on Sat Dec 16 08:02:31 GMT 2023
PRIMARY
MERCK INDEX
m8767
Created by admin on Sat Dec 16 08:02:31 GMT 2023 , Edited by admin on Sat Dec 16 08:02:31 GMT 2023
PRIMARY Merck Index
CAS
6091-05-0
Created by admin on Sat Dec 16 08:02:31 GMT 2023 , Edited by admin on Sat Dec 16 08:02:31 GMT 2023
PRIMARY