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Details

Stereochemistry ACHIRAL
Molecular Formula C15H14O
Molecular Weight 210.2711
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIHYDROCHALCONE

SMILES

O=C(CCC1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=QGGZBXOADPVUPN-UHFFFAOYSA-N
InChI=1S/C15H14O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-10H,11-12H2

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Evelynin, a cytotoxic benzoquinone-type Retro-dihydrochalcone from Tacca chantrieri.
2010-09-24
Chalcones and dihydrochalcones augment TRAIL-mediated apoptosis in prostate cancer cells.
2010-08-04
Soybean metabolites regulated in root hairs in response to the symbiotic bacterium Bradyrhizobium japonicum.
2010-08
Antispasmodic and antioxidant activities of fractions and bioactive constituent davidigenin isolated from Mascarenhasia arborescens.
2010-07-20
Cryptocaryone, a natural dihydrochalcone, induces apoptosis in human androgen independent prostate cancer cells by death receptor clustering in lipid raft and nonraft compartments.
2010-06
Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2.
2010-05-28
1-(2,6-Dihydr-oxy-4-methoxy-phen-yl)-3-phenyl-propan-1-one.
2010-04-21
Semi-synthesis of dihydrochalcone derivatives and their in vitro antimicrobial activities.
2010-04
Antioxidant activity of a red lentil extract and its fractions.
2009-12-23
Influence of apple polyphenols on inflammatory gene expression.
2009-10
Oxidation of the dihydrochalcone aspalathin leads to dimerization.
2009-08-12
Bioavailability of C-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas.
2009-08-12
Dietary phloridzin reduces blood glucose levels and reverses Sglt1 expression in the small intestine in streptozotocin-induced diabetic mice.
2009-06-10
New dihydrochalcone glycosides from Lithocarpus litseifolius and the phenomenon of C-H-->C-D exchange observed in NMR spectra of phenolic components.
2009-06
Phenolic contribution of South African herbal teas to a healthy diet.
2009-05
Bioactive flavonoids of the flowers of Butea monosperma.
2009-04
Absorption, metabolism, and excretion of cider dihydrochalcones in healthy humans and subjects with an ileostomy.
2009-03-11
Isoprenylated flavanones and dihydrochalcones from Macaranga trichocarpa.
2009-01
Dunaliine A, a new amino diketone from Desmos dunalii (Annonaceae).
2009
A new dihydrochalcone from dragon's blood, red resin of Dracaena cochinchinensis.
2008-12
Synthesis, cytotoxicity, and anti-Trypanosoma cruzi activity of new chalcones.
2008-10-09
Aspalathin, a flavonoid in Aspalathus linearis (rooibos), is absorbed by pig intestine as a C-glycoside.
2008-10
Prenylated dihydrochalcones from Boronia bipinnata that inhibit the malarial parasite enzyme target hemoglobinase II.
2008-08
Isolation and characterization of a novel glycosyltransferase that converts phloretin to phlorizin, a potent antioxidant in apple.
2008-08
Addition of the carbonyl oxygen to the ipso- or ortho-carbon atoms of the beta-phenyl ring followed by intersystem crossing and rapid relaxation to the ground-state ketones: a mechanism for beta-phenyl quenching of the first triplet excited states of derivatives of beta-phenylpropiophenone.
2008-06-19
Characterization of phenolic compounds in rooibos tea.
2008-05-14
The flavonoids of tomatoes.
2008-04-09
The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor.
2007-10-12
Evaluation of spectrophotometric methods for screening of green rooibos (Aspalathus linearis) and green honeybush (Cyclopia genistoides) extracts for high levels of Bio-active compounds.
2007-09-26
New dihydrochalcones and anti-platelet aggregation constituents from the leaves of Muntingia calabura.
2007-06
Concentrations and characteristics of procyanidins and other phenolics in apples during fruit growth.
2007-04
Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death.
2007-02
A new flavone xyloside and two new flavan-3-ol glucosides from Juniperus communis var. depressa.
2007-01
Characterization of a novel class of antimalarials and its applicability to plasmodial target identification.
2007
Efficient induction of apospory and apogamy in vitro in silver fern (Pityrogramma calomelanos L.).
2006-12
In situ flavonoid analysis by FT-Raman spectroscopy: identification, distribution, and quantification of aspalathin in green rooibos (Aspalathus linearis).
2006-11-15
An unusual homoisoflavanone and a structurally-related dihydrochalcone from Polygonum ferrugineum (Polygonaceae).
2006-10
Beccaridiol, an unusual 28-nortriterpenoid from the leaves of Diplectria beccariana.
2006-08
Anti-HIV-1 protease activity of compounds from Boesenbergia pandurata.
2006-03-15
The cloning and characterization of a soluble epoxide hydrolase in chicken.
2006-02
Antioxidant and pro-oxidant activities of aqueous extracts and crude polyphenolic fractions of rooibos (Aspalathus linearis).
2005-12-28
Mass spectrometric identification and quantification of glycosyl flavonoids, including dihydrochalcones with neutral loss scan mode.
2005-12-15
Metabolic engineering of plant cells for biotransformation of hesperedin into neohesperidin, a substrate for production of the low-calorie sweetener and flavor enhancer NHDC.
2005-12-14
Polyphenol profiles of apple juices.
2005-08
2',4'-Dihydroxy-3-methoxy-alpha,beta-dihydrochalcone and 2',4-dihydroxy-alpha,beta-dihydrochalcone: supramolecular structures formed by O-H...O, C-H...O and stacking interactions.
2005-06
Isolation and synthesis of a dimeric dihydrochalcone from Agapanthus africanus.
2005-05
Antioxidant activities of three dihydrochalcone glucosides from leaves of Lithocarpus pachyphyllus.
2005-04-09
Spasmolytic flavonoids from Syzygium samarangense (Blume) Merr. & L.M. Perry.
2005-03-25
Dihydrochalcones from the leaves of Pieris japonica.
2005-03
Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
1991-01-01
Patents
Name Type Language
NSC-12245
Preferred Name English
DIHYDROCHALCONE
Systematic Name English
1,3-DIPHENYL-PROPAN-1-ONE
Systematic Name English
1,3-DIPHENYLPROPAN-1-ONE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID7061481
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY
PUBCHEM
64802
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY
CHEBI
71231
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY
NSC
12245
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY
WIKIPEDIA
DIHYDROCHALCONE
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY
CAS
1083-30-3
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY
FDA UNII
H5W525SX7Q
Created by admin on Mon Mar 31 19:54:29 GMT 2025 , Edited by admin on Mon Mar 31 19:54:29 GMT 2025
PRIMARY