Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C19H21O6.K |
Molecular Weight | 384.4647 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[K+].[H][C@@]12CC[C@]3(O)C[C@]1(CC3=C)[C@@H](C([O-])=O)[C@]4([H])[C@@]5(C)[C@@H](O)C=C[C@@]24OC5=O
InChI
InChIKey=BGJIAUDTIACQSC-GLDAWBHVSA-M
InChI=1S/C19H22O6.K/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22;/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22);/q;+1/p-1/t10-,11+,12-,13-,16-,17+,18+,19-;/m1./s1
DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/8058529 | https://www.ncbi.nlm.nih.gov/pubmed/24079456Curator's Comment: Description was created based on several sources, including http://www.rarexoticseeds.com/en/gibberellic-acid-powder-ga3-90.html http://www.lifesciencesite.com/lsj/life0803/060_6326life0803_373_383.pdf
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8058529 | https://www.ncbi.nlm.nih.gov/pubmed/24079456
Curator's Comment: Description was created based on several sources, including http://www.rarexoticseeds.com/en/gibberellic-acid-powder-ga3-90.html http://www.lifesciencesite.com/lsj/life0803/060_6326life0803_373_383.pdf
Gibberellic acid was first discovered in Japan in 1935 as a result of the study of a condition common in rice plants called "foolish seedling" disease, which caused the plants to grow much taller than normal. The effects of gibberellins weren't widely understood until years later. Gibberellic acid, GA3 is a naturally occurring plant hormone that regulates the growth of plants, including triggering seed germination. Gibberellic Acid is not manufactured; it's a natural product extracted from the Gibberella fujikuroi fungus. There are over 100 known forms of gibberellic acid; GA3 is the most effective. Gibberellic acid (GA3) is used extensively in Egypt and other countries, to increase the growth of many fruits (such as strawberries and grapes) and vegetables (such as tomatoes, cabbages and cauliflower). Carcinogenic effect of Gibberellic acid has being demonstrated in several studies. Gibberellic acid increased the activity of testicular 3β-HSD and 17β-HSD and elevated testosterone content in rats, acting as an agonist of steroidogenesis in male rats. Gibberellic acid has being suggested to promote ulcer-healing, healing of surgical wounds or open fractures and treatment of bronchitis or thrombophlebitis in animals including humans.
CNS Activity
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: GO:0006694 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24079456 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Primary | Unknown Approved UseUnknown |
Sample Use Guides
In Vivo Use Guide
Sources: http://idosi.org/gjp/9(3)15/1.pdf
Rats:100 - 200 ppm of Gibberellic acid daily in drinking tap water for eight weeks, Gibberellic acid amount of each rat was about 3± 0.3mg - 6± 0.6 mg per
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24079456
150 ug of gibberellic acid increased the levels of StAR protein and ABP in the rat testis
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CFR |
21 CFR 172.725
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EPA PESTICIDE CODE |
43802
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C007842
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125-67-7
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H52L7VZB7S
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potassium gibberellate
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DTXSID6035605
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71299661
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204-749-6
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ACTIVE MOIETY
SUBSTANCE RECORD