Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H22N2O8 |
| Molecular Weight | 442.4187 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)[C@H]1[C@H]([C@H]2OC(=O)C3=C(O)C4=C(C=CC=C4O)C(C)=C23)[C@H](O)C(=O)C(C(N)=O)=C1O
InChI
InChIKey=DRKMHDAKULCOKQ-MLZJRGSSSA-N
InChI=1S/C22H22N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)20(32-22(12)31)13-15(24(2)3)17(27)14(21(23)30)19(29)18(13)28/h4-6,13,15,18,20,25-28H,1-3H3,(H2,23,30)/t13-,15-,18-,20-/m0/s1
alpha-apo-Oxytetracycline is the degradation product of Oxytetracycline. It exhibits greater toxicity compared with the parent compound. No significant differences in body weight were observed between rats in the control group and those in the group treated with alpha-apo-Oxytetracycline. No differences in hematological analyses were observed between rats in the control group and those in the group treated with alpha-apo-Oxytetracycline.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The degradation of oxytetracycline during thermal treatments of chicken and pig meat and the toxic effects of degradation products of oxytetracycline on rats. | 2015-05 |
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| A liquid chromatography-tandem mass spectrometry confirmatory assay for the simultaneous determination of several tetracyclines in milk considering keto-enol tautomerism and epimerization phenomena. | 2009-12-10 |
|
| Determination and fate of oxytetracycline and related compounds in oxytetracycline production wastewater and the receiving river. | 2008-01 |
|
| C(18) columns for the simultaneous determination of oxytetracycline and its related substances by reversed-phase high performance liquid chromatography and UV detection. | 2007-01-17 |
|
| Quantitative analysis of oxytetracycline and its impurities by LC-MS-MS. | 2004-02-04 |
|
| Susceptibility of Escherichia coli and Enterococcus faecium isolated from pigs and broiler chickens to tetracycline degradation products and distribution of tetracycline resistance determinants in E. coli from food animals. | 2003-08-29 |
|
| Characterisation of the abiotic degradation pathways of oxytetracyclines in soil interstitial water using LC-MS-MS. | 2003-03 |
|
| Determination of oxytetracycline and its degradation products by high-performance liquid chromatography-tandem mass spectrometry in manure-containing anaerobic test systems. | 2003-01-05 |
|
| Application of reversed-phase liquid chromatography and prepacked C18 cartridges for the analysis of oxytetracycline and related compounds. | 1996-03-03 |
Patents
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| Code System | Code | Type | Description | ||
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76971536
Created by
admin on Mon Mar 31 22:50:09 GMT 2025 , Edited by admin on Mon Mar 31 22:50:09 GMT 2025
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PRIMARY | |||
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1361013-47-9
Created by
admin on Mon Mar 31 22:50:09 GMT 2025 , Edited by admin on Mon Mar 31 22:50:09 GMT 2025
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ALTERNATIVE | |||
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DTXSID40940158
Created by
admin on Mon Mar 31 22:50:09 GMT 2025 , Edited by admin on Mon Mar 31 22:50:09 GMT 2025
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H4GV157YJQ
Created by
admin on Mon Mar 31 22:50:09 GMT 2025 , Edited by admin on Mon Mar 31 22:50:09 GMT 2025
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18695-01-7
Created by
admin on Mon Mar 31 22:50:09 GMT 2025 , Edited by admin on Mon Mar 31 22:50:09 GMT 2025
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PRIMARY |
SUBSTANCE RECORD
