Stereochemistry | ABSOLUTE |
Molecular Formula | C10H19NO5 |
Molecular Weight | 233.2616 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(CO)[C@@H](O)C(=O)NCCCC(O)=O
InChI
InChIKey=SBBDHANTMHIRGW-QMMMGPOBSA-N
InChI=1S/C10H19NO5/c1-10(2,6-12)8(15)9(16)11-5-3-4-7(13)14/h8,12,15H,3-6H2,1-2H3,(H,11,16)(H,13,14)/t8-/m0/s1
Hopantenic acid (homopantothenic acid) is a central nervous system depressant. Formulated as the calcium salt, it is used as a pharmaceutical drug in the Russian Federation under the brand name Pantogam. In Russia it is widely used to treat a variety of neurological, psychological and psychiatric conditions. The drug has been on the pharmaceutical market since 1979 and has been proven to be safe even for children from 3 years old upwards. Hopantenic acid is a natural forming substance, has some of the lowest side effects and considered to be very safe. Use Pantogam to treat a wide variety of cognitive and nervous system disorders with combined sedative and mild stimulant effect. Hopantenic acid is not approved for use in Europe or the United States. GABA receptor agonist.
CNS Activity
Approval Year
PubMed
Patents
Sample Use Guides
To be taken orally 15-30 minutes after breakfast and lunch.
Can be taken by children from 3 years old upwards.
For adults:
Single dose 250-1000 mg, daily dose 1500-3000 mg.
For children:
Single dose 250-500 mg, daily dose 750-2000 mg.
Course of treatment is 1-4 months, sometimes 6 months. A break of 3-6 months is required between courses of treatment.
Route of Administration:
Oral