Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H22O6 |
Molecular Weight | 310.3423 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCOC1=CC(OCC)=C(C=C1OCC)C(=O)CCC(O)=O
InChI
InChIKey=YPTFHLJNWSJXKG-UHFFFAOYSA-N
InChI=1S/C16H22O6/c1-4-20-13-10-15(22-6-3)14(21-5-2)9-11(13)12(17)7-8-16(18)19/h9-10H,4-8H2,1-3H3,(H,18,19)
DescriptionCurator's Comment: description was created based on several sources, including:
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00054798
http://www.ncbi.nlm.nih.gov/pubmed/864884
Curator's Comment: description was created based on several sources, including:
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00054798
http://www.ncbi.nlm.nih.gov/pubmed/864884
This medicine promotes secretion of the bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract (sphincter of hepatopancreatic ampulla etc.) to lower internal pressure of the gallbladder and bile duct. It improves the symptoms of the bile duct and pancreatic disease. It is usually used for improvement of cramp and bile secretion associated with cholelithiasis, cholecystitis, cholangitis, dyskinesia of the biliary tract or postcholecystectomy syndrome, or pain and gastrointestinal symptoms associated with chronic pancreatitis.
Side effects are nausea, constipation, abdominal bloating, diarrhea, rash, itch, etc.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: CHEMBL2023 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
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Palliative | SUPACAL Approved UseIt is usually used for improvement of cramp and bile secretion associated with cholelithiasis |
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Palliative | SUPACAL Approved UseIt is usually used for improvement of cramp and bile secretion associated with cholecystitis |
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Palliative | SUPACAL Approved UseIt is usually used for improvement of cramp and bile secretion associated with cholangitis |
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Palliative | SUPACAL Approved UseIt is usually used for improvement of cramp and bile secretion associated with postcholecystectomy syndrome |
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Classification Tree | Code System | Code | ||
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WHO-VATC |
QA03AX09
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NCI_THESAURUS |
C29698
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WHO-ATC |
A03AX09
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44532
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C66623
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100000077483
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m11017
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Trepibutone
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2719
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4358
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41826-92-0
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DTXSID6046634
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CHEMBL1725880
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DB13311
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5536
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H1187LU49Q
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SUB11236MIG
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ACTIVE MOIETY