Details
Stereochemistry | ACHIRAL |
Molecular Formula | C5H10O2 |
Molecular Weight | 102.1317 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CCCCC(O)=O
InChI
InChIKey=NQPDZGIKBAWPEJ-UHFFFAOYSA-N
InChI=1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
Valeric acid is a colorless, oily liquid with an unpleasant odor. It is highly corrosive and must be handled with care. Valeric acid is mainly used as a chemical intermediate to manufacture flavors and perfumes, synthetic lubricants, agricultural chemicals, and pharmaceuticals. It is also used as a flavoring aid in foods. Valeric acid is considered safe as a food additive by the World Health Organization.
Approval Year
PubMed
Title | Date | PubMed |
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[High-level production of poly (3-hydroxybutyrate-co-3-hydroxyvalerate) by feb-batch culture of Alcaligenes eutrophus]. | 2001 Sep |
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Estradiol valerate/dienogest. | 2002 |
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Effect of casein infusion in the rumen, duodenum or both sites on factors affecting forage intake and performance of dairy cows fed red clover-grass silage. | 2002 Apr |
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Comparative study of differentiation levels and valepotriate content of in vitro cultures and regenerated and wild plants of Valeriana edulis ssp.procera. | 2002 Apr |
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Effects of culture conditions on the production of polyhydroxyalkanoates by Azotobacter chroococcum H23 in media containing a high concentration of alpechín (wastewater from olive oil mills) as primary carbon source. | 2002 Aug 7 |
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A novel synthesis of (+)-biotin from L-cysteine. | 2002 Aug 9 |
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Severe hypertriglyceridemia and pancreatitis following hormone replacement prior to cryothaw transfer. | 2002 Feb |
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Development of a headspace solid-phase microextraction-gas chromatography-mass spectrometry method for the identification of odour-causing volatile compounds in packaging materials. | 2002 Jul 19 |
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Characterization of copolymer hydroxybutyrate/hydroxyvalerate from saponified vernonia, soybean, and "spent" frying oils. | 2002 Jul-Aug |
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1H and (13)C NMR spectroscopic analysis of human saliva. | 2002 Jun |
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A rapid selective extraction procedure for the outer membrane protein (OmpF) from Escherichia coli. | 2002 Jun |
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Ocular disposition of ganciclovir and its monoester prodrugs following intravitreal administration using microdialysis. | 2002 Jun |
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In vitro alterations in fecal short chain fatty acids and organic anions induced by the destruction of intestinal microflora under hypotonic and aerobic conditions. | 2002 Jun |
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Comparison of cryopreservation outcome with gonadotropin-releasing hormone agonists or antagonists in the collecting cycle. | 2002 Mar |
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Structural characterization of in vivo rat glutathione adducts and a hydroxylated metabolite of simvastatin hydroxy acid. | 2002 Mar |
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NutriDense and waxy corn hybrids: effects on site and extent of disappearance of nutrients in sheep. | 2002 May |
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Acylated triterpenoid saponins from the stem bark of Foetidia africana. | 2002 Nov |
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Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. | 2002 Oct 4 |
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Mass production of methane from food wastes with concomitant wastewater treatment. | 2002 Spring |
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Production of purified polyhydroxyalkanoates (PHAs) for applications in contact with blood. | 2003 |
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Liquefaction and methanization of solid and liquid coffee wastes by two phase anaerobic digestion process. | 2003 |
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Hydrogen production from wastewater by acidogenic granular sludge. | 2003 |
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Psychophysical evaluation of responses to pleasant and mal-odour stimulation in human subjects; adaptation, dose response and gender differences. | 2003 Apr |
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Effects of hydrochloric, valeric, and other volatile fatty acids on pathogenesis of ulcers in the nonglandular portion of the stomach of horses. | 2003 Apr |
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Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. | 2003 Apr 18 |
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Activation of neurons in trigeminal caudalis by noxious oral acidic or salt stimuli is not reduced by amiloride. | 2003 Apr 18 |
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Parameter identification of thermophilic anaerobic degradation of valerate. | 2003 Apr-Jun |
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Synthesis and cytotoxicity of new platinum(IV) complexes of mixed carboxylates. | 2003 Aug 1 |
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Conformationally constrained analogues of bleomycin A5. | 2003 Aug 27 |
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Enhanced biosynthesis of polyhydroxyalkanoates in a mutant strain of Rhizobium meliloti. | 2003 Jan |
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Eubacterium pyruvativorans sp. nov., a novel non-saccharolytic anaerobe from the rumen that ferments pyruvate and amino acids, forms caproate and utilizes acetate and propionate. | 2003 Jul |
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Efficacy of betamethasone valerate foam formulation in comparison with betamethasone dipropionate lotion in the treatment of mild-to-moderate alopecia areata: a multicenter, prospective, randomized, controlled, investigator-blinded trial. | 2003 Jul |
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Dynamics of the anaerobic process: effects of volatile fatty acids. | 2003 Jun 30 |
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Improvement of (+)-catechin inhibitory activity on human PMN respiratory burst by (+)-3-O-propionyl and (-)-3-O-valeryl substitution. | 2003 Mar |
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Lack of quinine-evoked activity in rat trigeminal subnucleus caudalis. | 2003 Mar |
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Optimizing the level of wet corn gluten feed in the diet of lactating dairy cows. | 2003 Mar |
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Left ventricular diastolic function assessment by tissue Doppler echocardiography in relation to hormonal replacement therapy in postmenopausal women with diastolic dysfunction. | 2003 Mar-Apr |
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Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high molar fractions of 3-hydroxyvalerate by a threonine-overproducing mutant of Alcaligenes sp. SH-69. | 2003 May |
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[Anti-arrhythmia activity of estradiol valerate and estradiol nitrate]. | 2003 May-Jun |
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Heterogeneous acylation of flax fibers. Reaction kinetics and surface properties. | 2003 May-Jun |
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Ruminal fermentation and bacterial protein synthesis of whole cottonseed coated with combinations of gelatinized corn starch and urea. | 2003 Nov |
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Pelleted beet pulp substituted for high-moisture corn: 3. Effects on ruminal fermentation, pH, and microbial protein efficiency in lactating dairy cows. | 2003 Nov |
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Mecamylamine reduces nicotine cross-desensitization of trigeminal caudalis neuronal responses to oral chemical irritation. | 2003 Nov 21 |
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Regulation of glucose-6-phosphatase gene expression in cultured hepatocytes and H4IIE cells by short-chain fatty acids: role of hepatic nuclear factor-4alpha. | 2003 Oct 17 |
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Kinetics of thermophilic, anaerobic oxidation of straight and branched chain butyrate and valerate. | 2003 Oct 20 |
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Synthesis, X-ray crystal structure, UV/visible linear and nonlinear (optical limiting) spectral properties of symmetrical and unsymmetrical porphyrazines with annulated 1,2,5-thiadiazole and 1,4-diamyloxybenzene moieties. | 2003 Sep 5 |
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The degradability of biodegradable plastics in aerobic and anaerobic waste landfill model reactors. | 2004 Jan |
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Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. | 2004 Jan 27 |
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Sequential feeding of glucose and valerate in a fed-batch culture of Ralstonia eutropha for production of poly(hydroxybutyrate-co-hydroxyvalerate) with high 3-hydroxyvalerate fraction. | 2004 Jan-Feb |
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Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids. | 2004 Mar |
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/26663903
1.5 mM valeric acid is an effective chemical reagent to increase mAb production in rCHO cells.
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CFR |
21 CFR 172.515
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JECFA EVALUATION |
VALERIC ACID
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203-677-2
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1370574
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278
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GZK92PJM7B
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DTXSID7021655
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7991
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17418
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C038780
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1546454
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m11360
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DB02406
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GZK92PJM7B
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100000127757
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SUB33854
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406833
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VALERIC ACID
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109-52-4
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5390
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valerate
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ACTIVE MOIETY
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)
SALT/SOLVATE (PARENT)