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Details

Stereochemistry RACEMIC
Molecular Formula C19H32N2O5
Molecular Weight 368.4678
Optical Activity ( + / - )
Defined Stereocenters 5 / 5
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,3A-DI-EPI-PERINDOPRIL, (±)-

SMILES

[H][C@@]12C[C@@H](N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@@]1([H])CCCC2)C(O)=O

InChI

InChIKey=IPVQLZZIHOAWMC-XFIYOXNOSA-N
InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13+,14-,15-,16+/m0/s1

HIDE SMILES / InChI

Description

(±)-2,3A-di-epi-Perindopril is a mixture of two isomers (S, SR, RR) and (R, RS, SS) which are both inactive epimers of the antihypertensive drug perindopril, although the (R, RS, SS) isomer possesses better activity.

Approval Year

Unknown
139594
Targets

Targets

Primary TargetPharmacologyConditionPotency
Inhibitor
8297
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Name Type Language
2,3A-DI-EPI-PERINDOPRIL, (±)-
Common Name English
(2SR,3ASR,7ARS)-1-((2RS)-2-(((1RS)-1-(ETHOXYCARBONYL)BUTYL)AMINO)PROPANOYL)OCTAHYDRO-1H-INDOLE-2-CARBOXYLIC ACID
Brand Name English
PERINDOPRIL TERT-BUTYLAMINE IMPURITY V [EP IMPURITY]
Common Name English
(±)-2,3A-DI-EPI-PERINDOPRIL
Common Name English
Code System Code Type Description
PUBCHEM
72941690
Created by admin on Sat Dec 16 10:41:52 UTC 2023 , Edited by admin on Sat Dec 16 10:41:52 UTC 2023
PRIMARY
FDA UNII
GR5K6963H1
Created by admin on Sat Dec 16 10:41:52 UTC 2023 , Edited by admin on Sat Dec 16 10:41:52 UTC 2023
PRIMARY
NIH
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