OMOCONAZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H17Cl3N2O2
Molecular Weight	423.72
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of OMOCONAZOLE

Structure Search

SMILES

C\C(N1C=CN=C1)=C(\OCCOC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3

InChI

InChIKey=JMFOSJNGKJCTMJ-ZHZULCJRSA-N

InChI=1S/C20H17Cl3N2O2/c1-14(25-9-8-24-13-25)20(18-7-4-16(22)12-19(18)23)27-11-10-26-17-5-2-15(21)3-6-17/h2-9,12-13H,10-11H2,1H3/b20-14-

HIDE SMILES / InChI

Description
Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html

Omoconazole is an azole antifungal drug, is used to treat candidiasis; dermatophytes and Pityriasis Versicolor

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Candida infections 20 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative		Approved 8429	Unknown Approved Use Unknown
Dermatomycosis 20 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative		Approved 8429	Unknown Approved Use Unknown
Pityriasis versicolor 4 Sources: http://www.onmeda.fr/medicament/fongamil-93327055.html	Curative		Approved 8429	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
Ultrastructural alterations of Candida albicans induced by a new imidazole antimycotic omoconazole nitrate.	1997	9194038

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Cream; Topical; Omoconazole Nitrate 1%

Route of Administration: Topical

In Vitro Use Guide

The treatment of growing Candida cultures with fungistatic doses (0.4 to 4 micrograms/ml) of omoconazole nitrate (OMZ) produced the formation of a chain or cluster of cells. Thickening of the cell wall and accumulation of electrondense vesicles in the wall were clearly observed

Name

Type

Language

OMOCONAZOLE

Official Name

English

Omoconazole [WHO-DD]

Common Name

English

(Z)-1-(2,4-DICHLORO-.BETA.-(2-(P-CHLOROPHENOXY)ETHOXY)-.ALPHA.-METHYLSTYRYL)IMIDAZOLE

Common Name

English

omoconazole [INN]

Common Name

English

OMOCONAZOLE [MI]

Common Name

English

1H-IMIDAZOLE, 1-(2-(2-(4-CHLOROPHENOXY)ETHOXY)-2-(2,4-DICHLOROPHENYL)-1-METHYLETHENYL)-, (Z)-

Common Name

English

Classification Tree Code System Code

WHO-ATC

G01AF16

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WHO-ATC

D01AC13

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WHO-VATC

QD01AC13

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WHO-VATC

QG01AF16

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NCI_THESAURUS

C514

Created by admin on Fri Dec 15 15:47:44 GMT 2023 , Edited by admin on Fri Dec 15 15:47:44 GMT 2023

Code System Code Type Description

DRUG CENTRAL

1991

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ChEMBL

CHEMBL2046550

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EVMPD

SUB09442MIG

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WIKIPEDIA

Omoconazole

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MERCK INDEX

m8211

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Merck Index

DRUG BANK

DB13684

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MESH

C050566

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RXCUI

32411

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RxNorm

SMS_ID

100000083319

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FDA UNII

GQ8ADD54E1

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NCI_THESAURUS

C74599

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EPA CompTox

DTXSID7057818

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PUBCHEM

3033988

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CAS

74512-12-2

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INN

4991

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ACTIVE MOIETY


					GQ8ADD54E1

SALT/SOLVATE (PARENT)


					15LTY5STY6

OMOCONAZOLE NITRATE