U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ABSOLUTE
Molecular Formula C24H29FO6
Molecular Weight 432.4819
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FLUPREDNIDENE ACETATE

SMILES

CC(=O)OCC(=O)[C@@]1(O)C(=C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C

InChI

InChIKey=DEFOZIFYUBUHHU-IYQKUMFPSA-N
InChI=1S/C24H29FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,17-19,28,30H,1,5-6,9,11-12H2,2-4H3/t17-,18-,19-,21-,22-,23-,24-/m0/s1

HIDE SMILES / InChI

Description

Fluprednidene (used in a form of fluprednidene 21-acetate) is a glucocorticoid developed for the treatment of inflammatory skin diseases. The drug is marketed under the name Decoderm in Europe.

Approval Year

Unknown
149,124

Conditions

ConditionModalityTargetsHighest PhaseProduct
Inflammatory skin diseases
5
 Primary
Approved
8,583
DECODERM

Doses

AEs

PubMed

Patents

JP2002542293A
14
JP4426729B2
8

Sample Use Guides

In Vivo Use Guide
Apply the cream to the affected skin areas once a day.
Route of Administration: Topical
In Vitro Use Guide
Unknown
ACTIVE MOIETY
Structure of FLUPREDNIDENE
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966