4-FORMYLCYCLOHEXENE

Details

Stereochemistry	RACEMIC
Molecular Formula	C7H10O
Molecular Weight	110.1537
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=CC1CCC=CC1

InChI

InChIKey=DCFDVJPDXYGCOK-UHFFFAOYSA-N

InChI=1S/C7H10O/c8-6-7-4-2-1-3-5-7/h1-2,6-7H,3-5H2

HIDE SMILES / InChI

Approval Year

PubMed

Title	Date	PubMed
Total synthesis of the immunosuppressant FR901483 via an amidoacrolein cycloaddition.	2001 Apr 19	11348175
The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands.	2003 Jun	14531871
Hydroxyisohexyl 3-cyclohexene carboxaldehyde- known as Lyral: quantitative aspects and risk assessment of an important fragrance allergen.	2003 Jun	14531869
Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products.	2005 Apr	15859994
Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix.	2005 Apr	15859993
Clinical update on contact allergy.	2005 Oct	16131919
Regular use of a hand cream can attenuate skin dryness and roughness caused by frequent hand washing.	2006 Feb 13	16476166
Selected important fragrance sensitizers in perfumes--current exposures.	2007 Apr	17343619
Frequency of and trends in fragrance allergy over a 15-year period.	2008 Mar	18279150
Recommendation to include fragrance mix 2 and hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) in the European baseline patch test series.	2008 Mar	18279149
Hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) is still a frequent allergen.	2008 Sep	18759910
Integrated, multidisciplinary care for hand eczema: design of a randomized controlled trial and cost-effectiveness study.	2009 Dec 1	19951404
Clinical relevance of positive patch test reactions to the 26 EU-labelled fragrances.	2009 Oct	19825093
The dose-response relationship between the patch test and ROAT and the potential use for regulatory purposes.	2009 Oct	19825091
Quantitative patch and repeated open application testing in hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitive-patients.	2009 Sep	19780773
Hydroxyisohexyl 3-cyclohexene carboxaldehyde allergy: relationship between patch test and repeated open application test thresholds.	2009 Sep	19486000
A new IFRA Standard on the fragrance ingredient, hydroxyisohexyl 3-cyclohexene carboxaldehyde.	2010 Apr	20433450
Fragrance contact allergy: a 4-year retrospective study.	2010 Aug	20573166
Fragrance allergy: assessing the safety of washed fabrics.	2010 Jun	20557341
Fragrance mix II in the baseline series contributes significantly to detection of fragrance allergy.	2010 Nov	20946455
Patch testing with fragrance mix II: results of the IVDK 2005-2008.	2010 Nov	20946454

Patents

Name

Type

Language

4-FORMYLCYCLOHEXENE

Systematic Name

English

1,2,5,6-TETRAHYDROBENZALDEHYDE

Systematic Name

English

3-CYCLOHEXENE-1-CARBOXALDEHYDE

Systematic Name

English

.DELTA.1-TETRAHYDROBENZALDEHYDE

Common Name

English

3-CYCLOHEXEN-1-ALDEHYDE [HSDB]

Common Name

English

CYCLOHEX-3-ENE-1-CARBALDEHYDE

Systematic Name

English

.DELTA.3-TETRAHYDROBENZALDEHYDE

Common Name

English

3-CYCLOHEXENE-1-CARBALDEHYDE

Systematic Name

English

NSC-16241

Code

English

1-CYCLOHEXENE-4-CARBOXALDEHYDE

Systematic Name

English

CYCLOHEXENE-4-CARBOXALDEHYDE

Systematic Name

English

3-CYCLOHEXENE-1-CARBOXALDEHYDE, (±)-

Systematic Name

English

1-FORMYL-3-CYCLOHEXENE

Systematic Name

English

1,2,3,6-TETRAHYDROBENZALDEHYDE

Systematic Name

English

4-CYCLOHEXENE-1-CARBOXALDEHYDE

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

202-858-3