GANGLEFENE

Details

Stereochemistry	UNKNOWN
Molecular Formula	C20H33NO3
Molecular Weight	335.4809
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CC(C)C(C)OC(=O)C1=CC=C(OCC(C)C)C=C1

InChI

InChIKey=GRALFSQRIBJAHX-UHFFFAOYSA-N

InChI=1S/C20H33NO3/c1-7-21(8-2)13-16(5)17(6)24-20(22)18-9-11-19(12-10-18)23-14-15(3)4/h9-12,15-17H,7-8,13-14H2,1-6H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/19430975 | https://link.springer.com/article/10.1007%2FBF01184898?LI=true
Curator's Comment: No abstract or full text available for the following articles: https://europepmc.org/abstract/med/13486531 | https://europepmc.org/abstract/med/13550627

Ganglefene is a coronary vasodilator. This n-cholinoblocker was originally studied for its effects on coronary circulation in angina pectoris. Animal studies have also shown shortened recovery period of motor functions after ganglefene administration. One rodent study showed that modulation of the n-cholinergic system by ganglefene in the developing fetal brain leads to changes in the quantitative and qualitative characteristics of elements of sexual behavior in pubescent offspring.

Approval Year

Name

Type

Language

GANGLEFENE

Official Name

English

3-DIETHYLAMINO-1,2-DIMETHYLPROPYL P-ISOBUTOXYBENZOATE

Common Name

English

GANGLEFENE [MI]

Common Name

English

P-ISOBUTOXYBENZOIC ACID 3-(DIETHYLAMINO)-1,2-DIMETHYLPROPYL ESTER

Common Name

English

Ganglefene [WHO-DD]

Common Name

English

4-(2-METHYLPROPOXY)BENZOIC ACID 3-(DIETHYLAMINO)-1,2-DIMETHYLPROPYL ESTER

Systematic Name

English

ganglefene [INN]

Common Name

English

P-ISOBUTOXYBENZOIC ACID .ALPHA.,.BETA.-DIMETHYL-.GAMMA.-DIETHYLAMINOPROPYL ESTER

Common Name

English

1,2-DIMETHYL-3-DIETHYLAMINOPROPYL P-ISOBUTOXYBENZOATE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66886