REPROMICIN

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C31H51NO8
Molecular Weight	565.7385
Optical Activity	UNSPECIFIED
Defined Stereocenters	11 / 11
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]2(O[C@H]1[C@@H](CC=O)C[C@@H](C)C(=O)\C=C\C(C)=C\[C@H](C)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]1C)O[C@H](C)C[C@@H]([C@H]2O)N(C)C

InChI

InChIKey=OBUIQEYZGMZXPJ-NPQHDNJNSA-N

InChI=1S/C31H51NO8/c1-9-27-20(4)14-18(2)10-11-25(34)19(3)15-23(12-13-33)30(22(6)26(35)17-28(36)39-27)40-31-29(37)24(32(7)8)16-21(5)38-31/h10-11,13-14,19-24,26-27,29-31,35,37H,9,12,15-17H2,1-8H3/b11-10+,18-14+/t19-,20+,21-,22+,23+,24+,26-,27-,29-,30-,31+/m1/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9083494 | https://www.ncbi.nlm.nih.gov/pubmed/9544934

Repromicin is a compound that was reported in the literature in the 1990’s. Repromicin derivatives were found to have potent antibacterial activity against the Gram-negative pathogen Pasteurella multocida and Pasteurella heamolytica (in vitro and in vivo). Subcutaneous administration (single dose) in animals was found to control induced pasteurellosis (in swine) and induced respiratory disease (in cattle).

Approval Year

Name

Type

Language

REPROMICIN

Official Name

English

REPROMICIN [USAN]

Common Name

English

16-ETHYL-4-HYDROXY-5,9,13,15-TETRAMETHYL-2,10-DIOXO-6-((3,4,6-TRIDEOXY-3-(DIMETHYLAMINO)-.BETA.-D-XYLO-HEXOPYRANOSYL)OXY)OXACYCLOHEXADECA-11,13-DIENE-7-ACETALDEHYDE

Common Name

English

SCH 16524

Code

English

CIRRAMYCIN A(SUB 1), 12,13-DEEPOXY-12,13-DIDEHYDRO-4'-DEOXY-

Common Name

English

repromicin [INN]

Common Name

English

SCH-16524

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C52588