ZIPEPROL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	MIXED
Molecular Formula	C23H32N2O3
Molecular Weight	384.5118
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ZIPEPROL

Structure Search

SMILES

COC(CN1CCN(CC(O)C(OC)C2=CC=CC=C2)CC1)C3=CC=CC=C3

InChI

InChIKey=VSTNNAYSCJQCQI-UHFFFAOYSA-N

InChI=1S/C23H32N2O3/c1-27-22(19-9-5-3-6-10-19)18-25-15-13-24(14-16-25)17-21(26)23(28-2)20-11-7-4-8-12-20/h3-12,21-23,26H,13-18H2,1-2H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/8889408 | https://www.ncbi.nlm.nih.gov/pubmed/9875445 | https://www.ncbi.nlm.nih.gov/pubmed/8934307 | https://www.ncbi.nlm.nih.gov/pubmed/10928682 |

Zipeprol is disubstituted piperazine that is marketed as a non-opioid antitussive in Europe, Asia, and South America. Zipeprol is not available in the United States or Canada and has been discontinued in Europe. Zipeprol is still available in some countries in Asia and South America. Zipeprol was demonstrated to have anticough effects in animal models, to be active as a blocker of histamine and cholinergic function, to be a potent local anesthetic and to possess bronchiospasmolytic actions. it had no remarkable cardiovascular or gastrointestinal actions in the rat or dog in comparison to codeine.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Recent trends of drug abuse and drug-associated deaths in Korea.	2004 Oct	15542749
Role of drug testing as an early warning programme: the experience of the Republic of Korea.	2005	21338024
Pyridoxine in clinical toxicology: a review.	2005 Apr	15756083

Name

Type

Language

ZIPEPROL

Official Name

English

Zipeprol [WHO-DD]

Common Name

English

(1-methoxy-3-[4-(2-methoxy-2-phenylethyl)piperazin-1-yl]-1-phenylpropan-2-ol

Systematic Name

English

DEA NO. 9873

Common Name

English

zipeprol [INN]

Common Name

English

ZIPEPROL [MI]

Common Name

English

ZO-TAB

Brand Name

English

Classification Tree Code System Code

DEA NO.

9873

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

NCI_THESAURUS

C66917

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

WHO-VATC

QR05DB15

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

WHO-ATC

R05DB15

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

Code System Code Type Description

PUBCHEM

36910

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

EPA CompTox

DTXSID00865732

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

MERCK INDEX

m11640

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

Merck Index

ChEMBL

CHEMBL2105497

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

MESH

C013341

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

EVMPD

SUB00167MIG

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

DRUG BANK

DB13564

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

INN

3212

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

CAS

34758-83-3

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

DRUG CENTRAL

2864

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

WIKIPEDIA

ZIPEPROL

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

NCI_THESAURUS

C66698

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

SMS_ID

100000078770

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

ECHA (EC/EINECS)

252-191-7

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

FDA UNII

G5MUV8139H

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

RXCUI

39969

Created by admin on Fri Dec 15 15:50:02 GMT 2023 , Edited by admin on Fri Dec 15 15:50:02 GMT 2023

PRIMARY

RxNorm

ACTIVE MOIETY


					G5MUV8139H

ZIPEPROL