Details
Stereochemistry | ACHIRAL |
Molecular Formula | C8H12N4O3S.ClH |
Molecular Weight | 280.732 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.COC(=S)NCCN1C(C)=NC=C1[N+]([O-])=O
InChI
InChIKey=RIUCUZVIVKJIFC-UHFFFAOYSA-N
InChI=1S/C8H12N4O3S.ClH/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2;/h5H,3-4H2,1-2H3,(H,9,16);1H
DescriptionSources: https://www.drugs.com/international/carnidazole.html
Sources: https://www.drugs.com/international/carnidazole.html
Carnidazole (trade name Spartrix) is an antiprotozoal drug of the nitroimidazole class used in veterinary medicine. Spartrix (Carnidazole) is indicated for oral treatment of trichomoniasis (canker) in ornamental and homing (non-food) pigeons.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL613161 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9786623 |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Curative | Unknown Approved UseUnknown |
|||
Curative | Spartrix Approved UseSpartrix (Carnidazole) is indicated for oral treatment of trichomoniasis (canker) in ornamental and homing (non-food) pigeons. Launch Date1989 |
PubMed
Title | Date | PubMed |
---|---|---|
Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry. | 2009 May 15 |
|
Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry. | 2009 Nov 13 |
Patents
Sample Use Guides
In Vivo Use Guide
Sources: http://www.jedds.com/shop/spartrix-tablets-50-count/
Pigeons: 1 tablet per adult pigeon and half tablet per young pigeon. A single dose is usually sufficient. In cases where pigeon does not respond within 3 days, it may be treated again.
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9786623
Carnidazole, dimetridazole, metronidazole and ornidazole showed a similar activity against isolates HF26, 79P and P2, with MLCs ranging from 1.9 to 7.8 ug/ml.
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ACTIVE MOIETY
SUBSTANCE RECORD