Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C8H12N4O3S.ClH |
| Molecular Weight | 280.732 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.COC(=S)NCCN1C(C)=NC=C1[N+]([O-])=O
InChI
InChIKey=RIUCUZVIVKJIFC-UHFFFAOYSA-N
InChI=1S/C8H12N4O3S.ClH/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2;/h5H,3-4H2,1-2H3,(H,9,16);1H
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
Target ID: CHEMBL613161 |
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Curative | Unknown Approved UseUnknown |
|||
| Curative | Spartrix Approved UseSpartrix (Carnidazole) is indicated for oral treatment of trichomoniasis (canker) in ornamental and homing (non-food) pigeons. Launch Date1989 |
Doses
| Dose | Population | Adverse events |
|---|---|---|
2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
Other AEs: Nausea, Vomitin... Other AEs: Nausea (grade 1, 13%) Sources: Vomitin (grade 1, 5%) Diarrhea (grade 1, 1%) Dry mouth (grade 1, 1%) Dizziness (grade 1, 1%) Headache (grade 1, 1%) |
AEs
| AE | Significance | Dose | Population |
|---|---|---|---|
| Diarrhea | grade 1, 1% | 2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
| Dizziness | grade 1, 1% | 2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
| Dry mouth | grade 1, 1% | 2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
| Headache | grade 1, 1% | 2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
| Nausea | grade 1, 13% | 2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
| Vomitin | grade 1, 5% | 2 g single, oral Highest studied dose |
unhealthy, ADULT Health Status: unhealthy Age Group: ADULT Sex: F Food Status: UNKNOWN Sources: |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Rapid multi-class multi-residue method for the confirmation of chloramphenicol and eleven nitroimidazoles in milk and honey by liquid chromatography-tandem mass spectrometry (LC-MS). | 2010-09 |
|
| Rapid confirmatory method for the determination of 11 nitroimidazoles in egg using liquid chromatography tandem mass spectrometry. | 2009-11-13 |
|
| Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry. | 2009-05-15 |
|
| Crystal structure of carnidazole form II from synchrotron X-ray powder diffraction: structural comparison with form I, the hydrated form and the low energy conformations in vacuo. | 2006-10 |
|
| Antiprotozoals effective in vitro against the scuticociliate fish pathogen Philasterides dicentrarchi. | 2002-06-03 |
Patents
Sample Use Guides
Pigeons: 1 tablet per adult pigeon and half tablet per young pigeon. A single dose is usually sufficient. In cases where pigeon does not respond within 3 days, it may be treated again.
Route of Administration:
Oral
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ACTIVE MOIETY
SUBSTANCE RECORD
