ACETYLPHENETURIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H16N2O3
Molecular Weight	248.2777
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCC(C(=O)NC(=O)NC(C)=O)C1=CC=CC=C1

InChI

InChIKey=GBPZSCQLDXUGNO-UHFFFAOYSA-N

InChI=1S/C13H16N2O3/c1-3-11(10-7-5-4-6-8-10)12(17)15-13(18)14-9(2)16/h4-8,11H,3H2,1-2H3,(H2,14,15,16,17,18)

HIDE SMILES / InChI

Description
Sources: http://rad-ar.or.jp/siori/english/kekka.cgi?n=35325

Acetylpheneturide (P-3981/Crampol) is used as an anticonvulsant in the treatment of epilepsy. It is usually used to treat convulsive attacks of epilepsy, psychomotor attacks and autonomic attacks. This medicine suppresses epileptic attacks by acting on the central nerves. The most commonly reported adverse reactions include generalized red rash.

CNS Activity

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
central nerves 1 Target ID: central nerves Sources: http://rad-ar.or.jp/siori/english/kekka.cgi?n=35325	Interacts 323

Conditions

Condition	Modality	Targets	Highest Phase	Product
Epilepsy 121 Sources: http://www.ncbi.nlm.nih.gov/pubmed/14004251	Primary		Basic research	CRAMPOL Powder Approved Use Unknown

PubMed

Title	Date	PubMed
[Treatment of refractory epilepsy with P-3981 (Crampol), a new anti-convulsant].	1962-04	14004251

Patents

Sample Use Guides

In Vivo Use Guide

for adults, start by taking the dose at 0.3 to 0.4 g, and for children, 0.1 to 0.2 g, three times a day after each meal

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

CRAMPOL

Preferred Name

English

ACETYLPHENETURIDE

Common Name

English

1-ACETYL-3-(2-PHENYLBUTYRYL)UREA

Systematic Name

English

N-((ACETYLAMINO)CARBONYL)-.ALPHA.-ETHYLBENZENEACETAMIDE

Systematic Name

English

(±)-1-ACETYL-3-(2-PHENYLBUTYRYL)UREA

Systematic Name

English

ACETYLPHENETURIDE [MI]

Common Name

English

ACETYLPHENETURIDE [JAN]

Common Name

English

Acetylpheneturide [WHO-DD]

Common Name

English

Code System Code Type Description

ChEMBL

CHEMBL2107062