Details
Stereochemistry | ACHIRAL |
Molecular Formula | FO3P.2H4N |
Molecular Weight | 134.0473 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[NH4+].[NH4+].[O-]P([O-])(F)=O
InChI
InChIKey=SAEOCANGOMBQSP-UHFFFAOYSA-N
InChI=1S/FH2O3P.2H3N/c1-5(2,3)4;;/h(H2,2,3,4);2*1H3
Monofluorophosphate (MFP) is an anion, which is a phosphate group with one oxygen atom substituted with a fluorine atom. Sodium Monofluorophosphate is intended to be used by both petitioners in food supplements as a source of fluoride in the forms of multi-vitamin, multi-mineral supplements, solid tablets or tablets dispersible in liquid. The toxic effects of Monofluorophosphate are attributable to the fluoride ion released by the in vivo hydrolysis of the parent compound. The Monofluorophosphate ion appears to play no role. The acute toxicity of Monofluorophosphate is somewhat less than that of NaF, due to the lesser availability of fluoride in the short term from Monofluorophosphate. In the long term, Monofluorophosphate produces virtually the same picture of renal effects and skeletal storage of fluoride as does NaF. Sodium Monofluorophosphate dissociates into sodium and Monofluorophosphate ions in the intestinal tract, the latter being absorbed mainly in the upper small intestine.
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL1075189 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6315234 |
3.4 mM [Ki] | ||
Target ID: CHEMBL5979 Sources: https://www.ncbi.nlm.nih.gov/pubmed/6315234 |
69.0 µM [Ki] |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Preventing | AMERFRESH Approved Usehelps potect against cavities. Launch Date1996 |
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10148997
Created by
admin on Sat Dec 16 20:11:17 GMT 2023 , Edited by admin on Sat Dec 16 20:11:17 GMT 2023
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FS46648QNC
Created by
admin on Sat Dec 16 20:11:17 GMT 2023 , Edited by admin on Sat Dec 16 20:11:17 GMT 2023
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14312-45-9
Created by
admin on Sat Dec 16 20:11:17 GMT 2023 , Edited by admin on Sat Dec 16 20:11:17 GMT 2023
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SUBSTANCE RECORD