Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H30O7 |
| Molecular Weight | 358.4266 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)COC(=O)CCCCCCCCCCC
InChI
InChIKey=DWKSHXDVQRZSII-SUMWQHHRSA-N
InChI=1S/C18H30O7/c1-2-3-4-5-6-7-8-9-10-11-14(20)24-12-13(19)17-15(21)16(22)18(23)25-17/h13,17,19,21-22H,2-12H2,1H3/t13-,17+/m0/s1
Ascorbyl laurate or L-ascorbyl-6-laurate is a lipophilic derivative of Vitamin C, a popular antioxidant. It was shown, that L-ascorbyl-6-laurate possessed a "double-faced" effect on free-radical-induced hemolysis of human erythrocytes: antioxidant and prooxidant, that might be useful for the safe use of lipophilic vitamin C.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A kinetic study of the synthesis of ascorbate fatty acid esters catalysed by immobilized lipase in organic media. | 2000 Aug |
|
| Evaluation of the free-radical-scavenging activity of diclofenac acid on the free-radical-induced haemolysis of human erythrocytes. | 2006 May |
|
| Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes. | 2007 Mar 1 |
|
| The antioxidant effect of hydroxyl-substituent Schiff bases on the free-radical-induced hemolysis of human erythrocytes. | 2007 Mar-Apr |
Patents
Sample Use Guides
It was investigated the effect of a high concentration of L-ascorbyl-6-laurate (VC-12) on 2,2'-azobis(2-amidinopropane hydrochloride) (AAPH)-induced haemolysis of human erythrocytes. The findings indicated that VC-12 was capable of protecting erythrocytes against AAPH-induced haemolysis when its concentration was below 60 microM. With an increase in the concentration of VC-12 and a decrease in the concentration of AAPH, VC-12 promoted haemolysis remarkably, the mechanism of which has been proposed as VC-12-mediated peroxidation.
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54702628
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FM8S1O02OG
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DTXSID50937256
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16690-40-7
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admin on Sat Dec 16 07:53:39 GMT 2023 , Edited by admin on Sat Dec 16 07:53:39 GMT 2023
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SUBSTANCE RECORD
