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Details

Stereochemistry ACHIRAL
Molecular Formula C22H25ClN2OS
Molecular Weight 400.965
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CLOPENTHIXOL, TRANS

SMILES

OCCN1CCN(CC\C=C2/C3=CC=CC=C3SC4=CC=C(Cl)C=C24)CC1

InChI

InChIKey=WFPIAZLQTJBIFN-BLLMUTORSA-N
InChI=1S/C22H25ClN2OS/c23-17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)27-22)5-3-9-24-10-12-25(13-11-24)14-15-26/h1-2,4-8,16,26H,3,9-15H2/b18-5+

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.
1967
Differential inhibition by dopamine D-1 and D-2 antagonists of circling behaviour induced by dopamine agonists in rats with unilateral 6-hydroxydopamine lesions.
1984 Jul 13
The antibacterial effect of selected phenothiazines and thioxanthenes on slow-growing mycobacteria.
1986 Dec
Prolonged oculogyric crisis on addition of nifedipine to neuroleptic medication regime.
1987 Jan
Zuclopenthixol and perphenazine in patients with acute psychotic states. A double-blind multicentre study.
1987 Jul
Zuclopenthixol and haloperidol/levomepromazine in the treatment of elderly patients with symptoms of aggressiveness and agitation: a double-blind, multi-centre study.
1989
Reversible lithium neurotoxicity at normal serum level may refer to intracranial pathology.
1989 May
[acute dystonias in combined abuse of cocaine and neuroleptics].
1994 Nov 26
Central D2 receptor occupancy and effects of zuclopenthixol acetate in humans.
1995 Nov
Paradoxical severe agitation induced by add-on high-doses quetiapine in schizo-affective disorder.
2014 May 15
Patents
Name Type Language
CLOPENTHIXOL, TRANS
Common Name English
1-PIPERAZINEETHANOL, 4-((3E)-3-(2-CHLORO-9H-THIOXANTHEN-9-YLIDENE)PROPYL)-
Systematic Name English
TRANS-CLOPENTHIXOL
Common Name English
(E)-CLOPENTHIXOL
Common Name English
.BETA.-CLOPENTHIXOL
Common Name English
Code System Code Type Description
EPA CompTox
53772-84-2
Created by admin on Tue Mar 06 11:31:03 UTC 2018 , Edited by admin on Tue Mar 06 11:31:03 UTC 2018
PRIMARY
PUBCHEM
5372683
Created by admin on Tue Mar 06 11:31:03 UTC 2018 , Edited by admin on Tue Mar 06 11:31:03 UTC 2018
PRIMARY SWITZERF
NCI_THESAURUS
C81091
Created by admin on Tue Mar 06 11:31:03 UTC 2018 , Edited by admin on Tue Mar 06 11:31:03 UTC 2018
PRIMARY
CAS
53772-84-2
Created by admin on Tue Mar 06 11:31:03 UTC 2018 , Edited by admin on Tue Mar 06 11:31:03 UTC 2018
PRIMARY