Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C29H32N6OS |
| Molecular Weight | 512.669 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CN2C=C(CC(=O)N3CCC4(CN(C4)[C@@H]5CCC6=CC(=CC=C56)C7=NC=NC(C)=C7)CC3)N=C2S1
InChI
InChIKey=ZIUDADZJCKGWKR-AREMUKBSSA-N
InChI=1S/C29H32N6OS/c1-19-11-25(31-18-30-19)22-3-5-24-21(12-22)4-6-26(24)35-16-29(17-35)7-9-33(10-8-29)27(36)13-23-15-34-14-20(2)37-28(34)32-23/h3,5,11-12,14-15,18,26H,4,6-10,13,16-17H2,1-2H3/t26-/m1/s1
Approval Year
| Name | Type | Language | ||
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Code | English | ||
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Systematic Name | English | ||
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Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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1334782-79-4
Created by
admin on Sat Dec 16 01:39:34 GMT 2023 , Edited by admin on Sat Dec 16 01:39:34 GMT 2023
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PRIMARY | |||
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DB14870
Created by
admin on Sat Dec 16 01:39:34 GMT 2023 , Edited by admin on Sat Dec 16 01:39:34 GMT 2023
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58438464
Created by
admin on Sat Dec 16 01:39:34 GMT 2023 , Edited by admin on Sat Dec 16 01:39:34 GMT 2023
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PF-05190457
Created by
admin on Sat Dec 16 01:39:34 GMT 2023 , Edited by admin on Sat Dec 16 01:39:34 GMT 2023
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PRIMARY | MedKoo CAT NO.: 522485, CAS NO.: 1334782-79-4Description: PF-5190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-5190457 potently increases insulin secretion in glucose-stimulated human islets. PF-5190457 has a superior balance of ghrelin receptor pharmacology and off-target selectivity. On the basis of its promising pharmacological and safety profile, PF-5190457 was advanced to human clinical trials. (last updated: 11/10/2015). | ||
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FF33NL9U5G
Created by
admin on Sat Dec 16 01:39:34 GMT 2023 , Edited by admin on Sat Dec 16 01:39:34 GMT 2023
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300000041357
Created by
admin on Sat Dec 16 01:39:34 GMT 2023 , Edited by admin on Sat Dec 16 01:39:34 GMT 2023
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PRIMARY |
ACTIVE MOIETY
METABOLITE LESS ACTIVE (PARENT)
