Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C28H29ClN2O3S |
| Molecular Weight | 509.059 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(O)C1=CN(C(=N1)C(C)(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)C4=CC=CC(=C4)S(C)(=O)=O
InChI
InChIKey=JLPURTXCSILYLW-UHFFFAOYSA-N
InChI=1S/C28H29ClN2O3S/c1-27(2,23-11-6-7-12-24(23)29)26-30-25(28(3,4)32)18-31(26)21-15-13-19(14-16-21)20-9-8-10-22(17-20)35(5,33)34/h6-18,32H,1-5H3
Approval Year
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Code | English | ||
|
Code | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
FB7ZTJ8M8A
Created by
admin on Sat Dec 16 05:12:11 GMT 2023 , Edited by admin on Sat Dec 16 05:12:11 GMT 2023
|
PRIMARY | |||
|
BMS-779788
Created by
admin on Sat Dec 16 05:12:11 GMT 2023 , Edited by admin on Sat Dec 16 05:12:11 GMT 2023
|
PRIMARY | MedKoo CAT NO: 522686; CAS NO: 918348-67-1; Description: BMS-779788, also known as XL-652, EXEL 04286652 and BMS-788, is potent partial LXR agonist with LXR.BETA. selectivity, which has an improved therapeutic window in the cynomolgus monkey compared with a full pan agonist. BMS-779788 induced LXR target genes in blood in vivo with an EC50 = 610 nM, a value similar to its in vitro blood gene induction potency. BMS-779788 was 29- and 12-fold less potent than the full agonist T0901317 in elevating plasma triglyceride and LDL cholesterol, respectively, with similar results for plasma cholesteryl ester transfer protein and apolipoprotein B. (last updated: 4/4/2016). | ||
|
59251511
Created by
admin on Sat Dec 16 05:12:11 GMT 2023 , Edited by admin on Sat Dec 16 05:12:11 GMT 2023
|
PRIMARY | |||
|
918348-67-1
Created by
admin on Sat Dec 16 05:12:11 GMT 2023 , Edited by admin on Sat Dec 16 05:12:11 GMT 2023
|
PRIMARY | |||
|
CHEMBL3545418
Created by
admin on Sat Dec 16 05:12:11 GMT 2023 , Edited by admin on Sat Dec 16 05:12:11 GMT 2023
|
PRIMARY |
ACTIVE MOIETY
