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Details

Stereochemistry RACEMIC
Molecular Formula C13H14Cl2O3
Molecular Weight 289.154
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CIPROFIBRATE

SMILES

CC(C)(OC1=CC=C(C=C1)C2CC2(Cl)Cl)C(O)=O

InChI

InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N
InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)

HIDE SMILES / InChI

Description

Ciprofibrate is an orally active phenoxyisobutyrate hypolipidemic compound. It acts by activating peroxisome proliferator activated receptor alpha. Ciprofibrate is efficacious for the correction of hyperlipidaemias.

Originator

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
58.0 µM [Ki]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
CIPROFIBRATE
PubMed

PubMed

TitleDatePubMed
Patents

Sample Use Guides

In Vivo Use Guide
The recommended dosage is one tablet (100mg ciprofibrate) per day.
Route of Administration: Oral
In Vitro Use Guide
0.25 mM ciprofibrate was found to increase the phosphorylation of epidermal-growth-factor receptor in isolated rat hepatocytes
Name Type Language
CIPROFIBRATE
EP   INN   MART.   MI   USAN   WHO-DD  
INN   USAN  
Official Name English
PROPANOIC ACID, 2-(4-(2,2-DICHLOROCYCLOPROPYL)PHENOXY)-2-METHYL-
Common Name English
CIPROFIBRATE [USAN]
Common Name English
CIPROFIBRATE [MART.]
Common Name English
CIPROFIBRATE [MI]
Common Name English
CIPROFIBRATE [WHO-DD]
Common Name English
2-(P-(2,2-DICHLOROCYCLOPROPYL)PHENOXY)-2-METHYLPROPIONIC ACID
Common Name English
WIN-35833
Code English
WIN 35833
Code English
CIPROFIBRATE [INN]
Common Name English
CIPROFIBRATE [EP]
Common Name English
Classification Tree Code System Code
WHO-VATC QC10AB08
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
WHO-ATC C10AB08
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
Code System Code Type Description
CAS
52214-84-3
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
PUBCHEM
2763
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY SWITZERF
NCI_THESAURUS
C87471
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
WIKIPEDIA
CIPROFIBRATE
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
ChEMBL
CHEMBL557555
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
MESH
C019304
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
ECHA (EC/EINECS)
257-744-6
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
MERCK INDEX
M3582
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY Merck Index
EPA CompTox
52214-84-3
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
EVMPD
SUB07469MIG
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY
RXCUI
21149
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY RxNorm
INN
4057
Created by admin on Tue Mar 06 12:21:56 UTC 2018 , Edited by admin on Tue Mar 06 12:21:56 UTC 2018
PRIMARY