U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H21FN2O3
Molecular Weight 428.4549
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PF-05105679

SMILES

C[C@@H](N(CC1=CC(=CC=C1)C(O)=O)C(=O)C2=CC3=C(C=CC=C3)N=C2)C4=CC=C(F)C=C4

InChI

InChIKey=BXNMZRPTQFVRFA-QGZVFWFLSA-N
InChI=1S/C26H21FN2O3/c1-17(19-9-11-23(27)12-10-19)29(16-18-5-4-7-21(13-18)26(31)32)25(30)22-14-20-6-2-3-8-24(20)28-15-22/h2-15,17H,16H2,1H3,(H,31,32)/t17-/m1/s1

HIDE SMILES / InChI

Approval Year

Targets

Primary TargetPharmacologyConditionPotency
103.0 nM [IC50]