U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Cl.Rb
Molecular Weight 117.371
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of RUBIDIUM CHLORIDE RB-82

SMILES

[Cl-].[82Rb+]

InChI

InChIKey=FGDZQCVHDSGLHJ-RYDPDVNUSA-M
InChI=1S/ClH.Rb/h1H;/q;+1/p-1/i;1-3

HIDE SMILES / InChI
Rubidium Rb-82 is a radioactive isotope of rubidium. It is widely used for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease. Rb-82 decays by positron emission and associated gamma emission with a physical half-life of 75 seconds. In biochemical behavior, it is analogous to potassium ion (K+) and is rapidly extracted by the myocardium proportional to the blood flow. Rb+ participates in the sodium-potassium (Na+/K+) ion exchange pumps that are present in cell membranes. 82 radioactivity in viable myocardium is higher than in infarcted tissue, reflecting intracellular retention. Rubidium 82 chloride was approved by the FDA and is marketed under a trade name Ruby-Fill and Cardiogen-82.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
CARDIOGEN-82

Approved Use

CardioGen-82 is a closed system used to produce rubidium Rb 82 chloride injection for intravenous use. Rubidium Rb 82 chloride injection is a radioactive diagnostic agent indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.

Launch Date

1989
Name Type Language
RUBIDIUM CHLORIDE RB-82
ORANGE BOOK  
Common Name English
RUBIDIUM CHLORIDE RB-82 [ORANGE BOOK]
Common Name English
CARDIOGEN-82
Brand Name English
RUBIDIUM CHLORIDE ((SUP 82)RBCL)
Common Name English
Rubidium (82 rb) chloride [WHO-DD]
Common Name English
RUBIDIUM RB-82 CHLORIDE
Common Name English
RUBY-FILL
Brand Name English
RUBIDIUM CHLORIDE RB 82 [USAN]
Common Name English
RUBIDIUM CHLORIDE RB 82
USAN  
USAN  
Official Name English
Classification Tree Code System Code
NDF-RT N0000177914
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
WHO-ATC V09GX04
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
WHO-VATC QV09GX04
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
NCI_THESAURUS C1446
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
Code System Code Type Description
SMS_ID
100000170860
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
NCI_THESAURUS
C47711
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
DRUG BANK
DBSALT002752
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
EPA CompTox
DTXSID60894902
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
LACTMED
Rubidium Chloride Rb 82
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
DAILYMED
F0Z746KRKQ
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
FDA UNII
F0Z746KRKQ
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
DRUG CENTRAL
5184
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
PUBCHEM
71357
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
USAN
DD-60
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110557
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
WIKIPEDIA
Rubidium-82 chloride
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
RXCUI
1367086
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY RxNorm
EVMPD
SUB185166
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY
CAS
132486-03-4
Created by admin on Fri Dec 15 15:59:11 GMT 2023 , Edited by admin on Fri Dec 15 15:59:11 GMT 2023
PRIMARY