Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C14H19N3O2.ClH |
| Molecular Weight | 297.78 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.CC(C)N[C@@H]1CCN2C(=O)NC3=CC=CC([C@H]1O)=C23
InChI
InChIKey=GIEFXLLRTJNFGT-LOCPCMAASA-N
InChI=1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19;/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19);1H/t11-,13-;/m1./s1
DescriptionCurator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3240917
Curator's Comment: Description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/3240917
Zilpaterol is an agonist of β2-adrenergic receptor. Zilpaterol exerts bronchospasmolytic action. Zilmax® (4.8% Zilpaterol hydrochloride) is used to increase rate of bodyweight gain, improve feed efficiency, and increase carcass leanness in cattle fed in confinement for a period of 20-40 consecutive days at the end of the feeding period before slaughter.
Originator
Sources: Frechet D., Plassard G., Brown N.L., Cltmence F., Nhdelec L. & Worcel M. (1984) Proceedings of the VlIIth International Symposium on Medicinal Chemistry, Swedish Pharmaceutical Press, Stockholm. Vol. I , pp. 90-93
Curator's Comment: reference retrieved from https://www.ncbi.nlm.nih.gov/pubmed/3240917
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pharmaceuticals, direct-fed microbials, and enzymes for enhancing growth and feed efficiency of beef. | 2003 Nov |
|
| Beta-adrenergic receptor agonists induce the release of granulocyte chemotactic protein-2, oncostatin M, and vascular endothelial growth factor from macrophages. | 2006 Jan |
|
| Identification of a probable new adrenergic agonist by nuclear magnetic resonance and mass spectrometry. | 2007 Mar 14 |
|
| Influence of beta-agonists (ractopamine HCl and zilpaterol HCl) on fecal shedding of Escherichia coli O157:H7 in feedlot cattle. | 2009 Dec |
|
| Synthesis and pharmacological characterization of beta2-adrenergic agonist enantiomers: zilpaterol. | 2009 Mar 26 |
|
| Effects of duration of zilpaterol hydrochloride supplementation on growth performance, carcass traits and meat quality of grain-fed cull cows. | 2010 Apr |
|
| Effect of zilpaterol hydrochloride supplementation on cutability and subprimal yield of beef steer carcasses. | 2010 May |
|
| Comparative effects of ractopamine hydrochloride and zilpaterol hydrochloride on growth performance, carcass traits, and longissimus tenderness of finishing steers. | 2010 May |
Sample Use Guides
Zilmax® (4.8% Zilpaterol hydrochloride) is used to increase rate of bodyweight gain, improve feed efficiency, and increase carcass leanness in cattle fed in confinement for a period of 20-40 consecutive days at the end of the feeding period before slaughter. Zilpaterol hydrochloride should be mixed into the feed at a level of 7.5 mg/kg on a 90% dry matter basis. This represents a dose of approximately 0.15 mg/kg bw or 60 to 90 mg
zilpaterol hydrochloride per animal per day.
Route of Administration:
Oral
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11507658
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m11594
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DBSALT001665
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119520-06-8
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ACTIVE MOIETY
SUBSTANCE RECORD
