FLUINDIONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H9FO2
Molecular Weight	240.2292
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

FC1=CC=C(C=C1)C2C(=O)C3=C(C=CC=C3)C2=O

InChI

InChIKey=NASXCEITKQITLD-UHFFFAOYSA-N

InChI=1S/C15H9FO2/c16-10-7-5-9(6-8-10)13-14(17)11-3-1-2-4-12(11)15(13)18/h1-8,13H

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/9465843 | https://www.onmeda.fr/medicament/previscan-93348413.html

Fluindione under the brand name Previscan, an oral anticoagulant, belongs to the vitamin K antagonist class and widely used in France. This drug is indicated to treat the thromboembolic diseases, the deep venous thrombosis, and pulmonary embolism.

Approval Year

PubMed

Title	Date	PubMed
[Drug hypersensitive syndrome caused by fluindione].	2001 Oct	11907960
Cholestatic hepatitis caused by fluindione.	2002 Nov-Dec	12666267
[Treatment of left intraventricular thrombosis with low molecular weight heparin].	2003 Apr	12741307
[Fluindione-induced acute exanthematous pustulosis with renal involvement].	2003 Dec	14724519
[Evaluation of an education program of patients undergoing oral anticoagulation treatment].	2003 Nov	14714343
[Spontaneous muscular haematomas in hemiplegic patients receiving anticoagulation therapy].	2004 Jul	15247856
Personalized versus non-personalized computerized decision support system to increase therapeutic quality control of oral anticoagulant therapy: an alternating time series analysis.	2004 Sep 29	15456515
Can cryoglobulins interfere with the measurement of IgM antiphosphatidylethanolamine antibodies by ELISA?	2007	16766022
Potentiation of fluindione or warfarin by dexamethasone in multiple myeloma and AL amyloidosis.	2007 Oct	17692552
Self-control of long-term oral anticoagulation using a point-of-care device.	2008 Nov-Dec	19059561
[Necrotizing folliculitis in Behçet's disease].	2009 Mar	18635291
Budd-Chiari syndrome as a vascular complication of amebic liver abscess.	2009 Nov	19861608
Ischemic Stroke of the Artery of Percheron with Normal Initial MRI: A Case Report.	2010	20300550
[Thrombosis of the inferior vena cava revealing primary antiphospholipid syndrome: a case report].	2010 Feb	19969435
[Usefulness of JAK2 mutation assessment in recurrent deep venous thrombosis].	2010 Jul	20362361
[Glycopeptide-induced cutaneous adverse reaction].	2010 May	20470913
Immunoallergic adverse effects of fluindione.	2010 Nov	21284358

Sample Use Guides

In Vivo Use Guide

20 mg at the beginning with 5 mg increments

Route of Administration: Oral

Name

Type

Language

FLUINDIONE

Official Name

English

FLUINDIONE [MART.]

Common Name

English

PREVISCCAN

Brand Name

English

2-(P-FLUOROPHENYL)-1,3-INDANDIONE

Common Name

English

Fluindione [WHO-DD]

Common Name

English

fluindione [INN]

Common Name

English

FLUINDIONE [MI]

Common Name

English

Classification Tree Code System Code

WHO-ATC

B01AA12