U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C13H16N2O2S
Molecular Weight 264.343
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of THIALBARBITAL

SMILES

C=CCC2(C1CCCC=C1)C(=O)NC(=S)NC2=O

InChI

InChIKey=PXLVRFQEBVNJOH-UHFFFAOYSA-N
InChI=1S/C13H16N2O2S/c1-2-8-13(9-6-4-3-5-7-9)10(16)14-12(18)15-11(13)17/h2,4,6,9H,1,3,5,7-8H2,(H2,14,15,16,17,18)

HIDE SMILES / InChI
THIALBARBITAL is a barbiturate derivative with sedative effects. Barbiturates have hypnotic properties and are used as active moiety on central nervous system. Thialbarbital was synthesized in the 1960s. It was used primarily as a surgical anesthesia. Thialbarbital causes marked depression of the activity of the reticular formation and only slight depression of cortical activity. Thialbarbital is short acting and has less of a tendency to induce respiratory depression than other barbiturate derivatives such as pentobarbital.

Approval Year

Name Type Language
THIALBARBITAL
INN   MI   WHO-DD  
INN  
Official Name English
THIALBARBITONE
Common Name English
THIALBARBITAL [MI]
Common Name English
Thialbarbital [WHO-DD]
Common Name English
5-ALLYL-5-(2-CYCLOHEXEN-1-YL)-2-THIOBARBITURIC ACID
Systematic Name English
thialbarbital [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C67084
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
Code System Code Type Description
CAS
467-36-7
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
ChEMBL
CHEMBL2104657
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
SMS_ID
100000082396
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
INN
14
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
EVMPD
SUB10966MIG
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
DRUG CENTRAL
3595
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
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FDA UNII
ENV72C33QD
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
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EPA CompTox
DTXSID90861960
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
NCI_THESAURUS
C77631
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
PUBCHEM
3032306
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY
ECHA (EC/EINECS)
207-390-3
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
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MERCK INDEX
m10714
Created by admin on Sat Dec 16 17:51:47 GMT 2023 , Edited by admin on Sat Dec 16 17:51:47 GMT 2023
PRIMARY Merck Index