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Details

Stereochemistry ABSOLUTE
Molecular Formula C37H42N2O7
Molecular Weight 626.7386
Optical Activity UNSPECIFIED
Defined Stereocenters 7 / 7
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENDACORT

SMILES

[H][C@@]12CC[C@](O)(C(=O)COC(=O)COC3=NN(CC4=CC=CC=C4)C5=C3C=CC=C5)[C@@]1(C)C[C@H](O)[C@@]6([H])[C@@]2([H])CCC7=CC(=O)CC[C@]67C

InChI

InChIKey=DYVIEGCPUPGXOH-HGGPGNIHSA-N
InChI=1S/C37H42N2O7/c1-35-16-14-25(40)18-24(35)12-13-26-28-15-17-37(44,36(28,2)19-30(41)33(26)35)31(42)21-45-32(43)22-46-34-27-10-6-7-11-29(27)39(38-34)20-23-8-4-3-5-9-23/h3-11,18,26,28,30,33,41,44H,12-17,19-22H2,1-2H3/t26-,28-,30-,33+,35-,36-,37-/m0/s1

HIDE SMILES / InChI
Bendacort is an ester of glucocorticosteroid hydrocortisone and non-steroidal anti-inflammatory drug bendazac. In vivo studies demonstrated that bendacort has a wider spectrum of anti-inflammatory effects than bendazac or hydrocortisone alone: bendacort acts on responses with a necrotic evolution where tissue damage predominates, and in cases where the reaction of tissue defense predominates, as for example in the healing of wounds. Bendacort was marketed in Italy under tradename Versacort for the treatment of sensitive steroid dermatoses, contact eczema, dyshidrosis, insect bites.

Approval Year

Patents

Patents

Name Type Language
BENDACORT
MART.  
Common Name English
CORTAZAC
Common Name English
AF-2071
Common Name English
HYDROCORTISONE BENDAZAC
Common Name English
PREGN-4-ENE-3,20-DIONE, 11,17-DIHYDROXY-21-((2-((1-(PHENYLMETHYL)-1H-INDAZOL-3-YL)OXY)ACETYL)OXY)-, (11.BETA.)-
Common Name English
BENDACORT [MART.]
Common Name English
PREGN-4-ENE-3,20-DIONE, 11,17-DIHYDROXY-21-((((1-(PHENYLMETHYL)-1H-INDAZOL-3-YL)OXY)ACETYL)OXY)-, (11.BETA.)-
Common Name English
Code System Code Type Description
PUBCHEM
93288
Created by admin on Fri Dec 15 19:39:52 GMT 2023 , Edited by admin on Fri Dec 15 19:39:52 GMT 2023
PRIMARY
CAS
53716-43-1
Created by admin on Fri Dec 15 19:39:52 GMT 2023 , Edited by admin on Fri Dec 15 19:39:52 GMT 2023
PRIMARY
EPA CompTox
DTXSID00968474
Created by admin on Fri Dec 15 19:39:52 GMT 2023 , Edited by admin on Fri Dec 15 19:39:52 GMT 2023
PRIMARY
FDA UNII
EF5DH3EFH5
Created by admin on Fri Dec 15 19:39:52 GMT 2023 , Edited by admin on Fri Dec 15 19:39:52 GMT 2023
PRIMARY
ECHA (EC/EINECS)
258-710-3
Created by admin on Fri Dec 15 19:39:52 GMT 2023 , Edited by admin on Fri Dec 15 19:39:52 GMT 2023
PRIMARY